ID   FEPB_ECOL6              Reviewed;         318 AA.
AC   P0AEL7; P14609;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Ferric enterobactin-binding periplasmic protein FepB {ECO:0000250|UniProtKB:P0AEL6};
DE   Flags: Precursor;
GN   Name=fepB; OrderedLocusNames=c0679;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Part of the ABC transporter complex FepBDGC involved in
CC       ferric enterobactin uptake (By similarity). Binds ferric enterobactin
CC       (By similarity). {ECO:0000250|UniProtKB:P0AEL6}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (FepC),
CC       two transmembrane proteins (FepD and FepG) and a solute-binding protein
CC       (FepB). {ECO:0000250|UniProtKB:P0AEL6}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250|UniProtKB:P0AEL6}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 8 family.
CC       {ECO:0000305}.
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DR   EMBL; AE014075; AAN79154.1; -; Genomic_DNA.
DR   RefSeq; WP_001234311.1; NC_004431.1.
DR   AlphaFoldDB; P0AEL7; -.
DR   BMRB; P0AEL7; -.
DR   SMR; P0AEL7; -.
DR   STRING; 199310.c0679; -.
DR   EnsemblBacteria; AAN79154; AAN79154; c0679.
DR   KEGG; ecc:c0679; -.
DR   eggNOG; COG4592; Bacteria.
DR   HOGENOM; CLU_038034_4_0_6; -.
DR   OMA; DESFMFI; -.
DR   BioCyc; ECOL199310:C0679-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   InterPro; IPR002491; ABC_transptr_periplasmic_BD.
DR   Pfam; PF01497; Peripla_BP_2; 1.
DR   PROSITE; PS50983; FE_B12_PBP; 1.
PE   3: Inferred from homology;
KW   Ion transport; Iron; Iron transport; Periplasm; Signal; Transport.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..318
FT                   /note="Ferric enterobactin-binding periplasmic protein
FT                   FepB"
FT                   /id="PRO_0000044625"
FT   DOMAIN          48..318
FT                   /note="Fe/B12 periplasmic-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00344"
SQ   SEQUENCE   318 AA;  34283 MW;  807676D03A508079 CRC64;
     MRLAPLYRNA LLLTGLLLSG IAAVQAADWP RQITDSRGTH TLESQPQRIV STSVTLTGSL
     LAIDAPVIAS GATTPNNRVA DDQGFLRQWS KVAKERKLQR LYIGEPSAEA VAAQMPDLIL
     ISATGGDSAL ALYDQLSTIA PTLIINYDDK SWQSLLTQLG EITGHEKQAA ERIAQFDKQL
     AAAKEQIKLP PQPVTAIVYT AAAHSANLWT PESAQGQMLE QLGFTLAKLP AGLNASQSQG
     KRHDIIQLGG ENLAAGLNGE SLFLFAGDQK DADAIYANPL LAHLPAVQNK QVYALGTETF
     RLDYYSAMQV LDRLKALF