FER1_DESAF
ID FER1_DESAF Reviewed; 65 AA.
AC P00210;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Ferredoxin-1;
DE AltName: Full=Ferredoxin I;
DE Short=FdI;
GN Name=fd1;
OS Desulfocurvibacter africanus (Desulfovibrio africanus).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC Desulfovibrionaceae; Desulfocurvibacter.
OX NCBI_TaxID=873;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 19996 / DSM 2603 / NCIMB 8401 / Benghazi;
RA Cavazza C.C., Hatchikian E.C.;
RT "Investigations of the role of surface residues of ferredoxin I from
RT Desulfovibrio africanus in the interaction with its redox partner, the
RT pyruvate ferredoxin:oxidoreductase.";
RL Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP PROTEIN SEQUENCE OF 2-65.
RC STRAIN=ATCC 19996 / DSM 2603 / NCIMB 8401 / Benghazi;
RX PubMed=7126685; DOI=10.1016/s0300-9084(82)80166-1;
RA Bruschi M., Hatchikian E.C.;
RT "Non-heme iron proteins of Desulfovibrio: the primary structure of
RT ferredoxin I from Desulfovibrio africanus.";
RL Biochimie 64:503-507(1982).
RN [3]
RP X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS), AND SEQUENCE REVISION.
RX PubMed=7803404; DOI=10.1021/bi00255a022;
RA Seri A., Housset D., Serre L., Bonicel J., Hatchikian E.C., Frey M.,
RA Roth M.;
RT "Crystal structure of the ferredoxin I from Desulfovibrio africanus at 2.3-
RT A resolution.";
RL Biochemistry 33:15408-15417(1994).
RN [4]
RP STRUCTURE BY NMR.
RX PubMed=9533888; DOI=10.1006/jmbi.1998.1631;
RA Davy S.L., Osborne M.J., Moore G.R.;
RT "Determination of the structure of oxidised Desulfovibrio africanus
RT ferredoxin I by 1H NMR spectroscopy and comparison of its solution
RT structure with its crystal structure.";
RL J. Mol. Biol. 277:683-706(1998).
CC -!- FUNCTION: Ferredoxins are iron-sulfur proteins that transfer electrons
CC in a wide variety of metabolic reactions.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Note=Binds 1 [4Fe-4S] cluster.;
CC -!- SUBUNIT: Homodimer.
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DR EMBL; AJ489482; CAD33799.1; -; Genomic_DNA.
DR PIR; A56050; FEDV1A.
DR PDB; 1DAX; NMR; -; A=2-65.
DR PDB; 1DFD; NMR; -; A=2-65.
DR PDB; 1FXR; X-ray; 2.30 A; A/B=2-65.
DR PDBsum; 1DAX; -.
DR PDBsum; 1DFD; -.
DR PDBsum; 1FXR; -.
DR AlphaFoldDB; P00210; -.
DR SMR; P00210; -.
DR EvolutionaryTrace; P00210; -.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR InterPro; IPR001080; 3Fe4S_ferredoxin.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR PRINTS; PR00352; 3FE4SFRDOXIN.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; 4Fe-4S; Direct protein sequencing; Electron transport; Iron;
KW Iron-sulfur; Metal-binding; Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|PubMed:7126685"
FT CHAIN 2..65
FT /note="Ferredoxin-1"
FT /id="PRO_0000159194"
FT DOMAIN 3..31
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT BINDING 12
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000269|PubMed:7803404"
FT BINDING 15
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000269|PubMed:7803404"
FT BINDING 18
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000269|PubMed:7803404"
FT BINDING 55
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000269|PubMed:7803404"
FT STRAND 4..7
FT /evidence="ECO:0007829|PDB:1FXR"
FT TURN 9..11
FT /evidence="ECO:0007829|PDB:1FXR"
FT HELIX 17..21
FT /evidence="ECO:0007829|PDB:1FXR"
FT TURN 23..25
FT /evidence="ECO:0007829|PDB:1FXR"
FT STRAND 26..28
FT /evidence="ECO:0007829|PDB:1FXR"
FT TURN 30..32
FT /evidence="ECO:0007829|PDB:1FXR"
FT STRAND 35..38
FT /evidence="ECO:0007829|PDB:1FXR"
FT HELIX 40..42
FT /evidence="ECO:0007829|PDB:1DAX"
FT HELIX 45..54
FT /evidence="ECO:0007829|PDB:1FXR"
FT STRAND 55..57
FT /evidence="ECO:0007829|PDB:1DAX"
FT STRAND 60..63
FT /evidence="ECO:0007829|PDB:1FXR"
SQ SEQUENCE 65 AA; 7333 MW; 2B48BF6C20353D93 CRC64;
MARKFYVDQD ECIACESCVE IAPGAFAMDP EIEKAYVKDV EGASQEEVEE AMDTCPVQCI
HWEDE
