FER7_ZYMTI
ID FER7_ZYMTI Reviewed; 648 AA.
AC F9X9V3;
DT 07-OCT-2020, integrated into UniProtKB/Swiss-Prot.
DT 19-OCT-2011, sequence version 1.
DT 25-MAY-2022, entry version 38.
DE RecName: Full=Siderophore transporter MYCGRDRAFT_70577 {ECO:0000303|PubMed:28818040};
DE AltName: Full=Ferrichrome A-like siderophore biosynthesis protein MYCGRDRAFT_70577 {ECO:0000303|PubMed:28818040};
GN ORFNames=MYCGRDRAFT_70577;
OS Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch
OS fungus) (Septoria tritici).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX NCBI_TaxID=336722;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 115943 / IPO323;
RX PubMed=21695235; DOI=10.1371/journal.pgen.1002070;
RA Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F.,
RA Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A.,
RA Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A.,
RA Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., Cools H.J.,
RA Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B.,
RA van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B.,
RA Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A.,
RA Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R.,
RA Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J.,
RA Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H.,
RA de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H.,
RA Oliver R.P., Grigoriev I.V., Kema G.H.J.;
RT "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola
RT reveals dispensome structure, chromosome plasticity, and stealth
RT pathogenesis.";
RL PLoS Genet. 7:E1002070-E1002070(2011).
RN [2]
RP FUNCTION.
RX PubMed=28818040; DOI=10.1186/s12864-017-3969-y;
RA Cairns T., Meyer V.;
RT "In silico prediction and characterization of secondary metabolite
RT biosynthetic gene clusters in the wheat pathogen Zymoseptoria tritici.";
RL BMC Genomics 18:631-631(2017).
CC -!- FUNCTION: Siderophore transporter; part of the gene cluster 14 that
CC mediates the biosynthesis of a ferrichrome A-like siderophors which may
CC contribute to organismal virulence. {ECO:0000305|PubMed:28818040}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000305}.
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DR EMBL; CM001199; EGP87767.1; -; Genomic_DNA.
DR RefSeq; XP_003852791.1; XM_003852743.1.
DR AlphaFoldDB; F9X9V3; -.
DR STRING; 1047171.Mycgr3P70577; -.
DR EnsemblFungi; Mycgr3T70577; Mycgr3P70577; Mycgr3G70577.
DR GeneID; 13397142; -.
DR KEGG; ztr:MYCGRDRAFT_70577; -.
DR VEuPathDB; FungiDB:ZTRI_4.4; -.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_012970_2_2_1; -.
DR InParanoid; F9X9V3; -.
DR Proteomes; UP000008062; Chromosome 4.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR SUPFAM; SSF103473; SSF103473; 2.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..648
FT /note="Siderophore transporter MYCGRDRAFT_70577"
FT /id="PRO_0000451096"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 205..225
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 236..256
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 336..356
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 409..429
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 438..458
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 468..488
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 500..520
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 578..598
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..27
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..49
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 648 AA; 70597 MW; 9DCC5D691CCA4220 CRC64;
MRTSSESHSR SDAFNGKNDA SQVTVDSDSA SKDHHDHDHH HKDTSINERQ SQHVHQQAGV
SKVEAFNKAL YQSGPSGRLL LYVLVASLAL TMFAYALDQG ITYQFNAIAS SDFSQHASLG
AVNTASSIIR AISKPFLGKL SDITSRPTTY VVVLVVYAVG FAVAASSQGL AAYIVGASFT
AFGKSGLDLL SDIIVGDLTP LEWRAFWSGM LATPFLITTF INGFISDAFV PNNWRWGLGM
FAIMMPVLLT PAIWTLYGMQ LKAAKMGMVS MGDSGLARKD GVKVQGMQQY LPMARSIAVE
MDLIGLLLLG LAFSLILLAL NLAPASNGGW SNPSMIAMLV IGFVILGLFI AYEALLAPVP
ITPKRILTNK AFLCALTVDV FNQMASATRN NYWSSYIYII KPWSNYVWTI FIGTTTLTLC
TMSPIGGLIH RATHRYKTLM VIGAIIKLIG YGVGLDGNSR STLSTARLAV SQVMLGMGAW
TVIGARVGSQ ASVPHQDLSV VISVMSLWST MASSIGSTIA ATIWQDRMLN YMREECPPST
PEATLKKIYG SIKTLKTKYD WEDPVRMGAI RAYTRTNGII LAVSLVLAAV PVVFSCLMPN
YYLGKQQNAV TNTDVLGERT EVPRRVEEPT NGKPSLWQRV KRGYYKET
