ID   FER_APHSA               Reviewed;          97 AA.
AC   P00250;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Ferredoxin-1;
DE   AltName: Full=Ferredoxin I;
OS   Aphanothece sacrum.
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Chroococcales;
OC   Aphanothecaceae; Aphanothece.
OX   NCBI_TaxID=1122;
RN   [1]
RP   PROTEIN SEQUENCE OF 2-97.
RX   PubMed=818078; DOI=10.1093/oxfordjournals.jbchem.a131076;
RA   Hase T., Wada K., Matsubara H.;
RT   "Amino acid sequence of the major component of Aphanothece sacrum
RT   ferredoxin.";
RL   J. Biochem. 79:329-343(1976).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS).
RX   PubMed=2123937; DOI=10.1016/s0022-2836(05)80330-4;
RA   Tsukihara T., Fukuyama K., Mizushima M., Harioka T., Kusunoki M.,
RA   Katsube Y., Hase T., Matsubara H.;
RT   "Structure of the [2Fe-2S] ferredoxin I from the blue-green alga
RT   Aphanothece sacrum at 2.2-A resolution.";
RL   J. Mol. Biol. 216:399-410(1990).
CC   -!- FUNCTION: Ferredoxins are iron-sulfur proteins that transfer electrons
CC       in a wide variety of metabolic reactions.
CC   -!- COFACTOR:
CC       Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC       Note=Binds 1 [2Fe-2S] cluster.;
CC   -!- SIMILARITY: Belongs to the 2Fe2S plant-type ferredoxin family.
CC       {ECO:0000305}.
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DR   PIR; A00254; FEAH.
DR   PDB; 1FXI; X-ray; 2.20 A; A/B/C/D=2-97.
DR   PDB; 3AV8; X-ray; 1.46 A; A/B/C/D=2-97.
DR   PDBsum; 1FXI; -.
DR   PDBsum; 3AV8; -.
DR   AlphaFoldDB; P00250; -.
DR   SMR; P00250; -.
DR   EvolutionaryTrace; P00250; -.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd00207; fer2; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR   InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR   InterPro; IPR006058; 2Fe2S_fd_BS.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR010241; Fd_pln.
DR   Pfam; PF00111; Fer2; 1.
DR   SUPFAM; SSF54292; SSF54292; 1.
DR   TIGRFAMs; TIGR02008; fdx_plant; 1.
DR   PROSITE; PS00197; 2FE2S_FER_1; 1.
DR   PROSITE; PS51085; 2FE2S_FER_2; 1.
PE   1: Evidence at protein level;
KW   2Fe-2S; 3D-structure; Direct protein sequencing; Electron transport; Iron;
KW   Iron-sulfur; Metal-binding; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:818078"
FT   CHAIN           2..97
FT                   /note="Ferredoxin-1"
FT                   /id="PRO_0000189306"
FT   DOMAIN          4..94
FT                   /note="2Fe-2S ferredoxin-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00465"
FT   BINDING         40
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00465,
FT                   ECO:0000269|PubMed:2123937"
FT   BINDING         45
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00465,
FT                   ECO:0000269|PubMed:2123937"
FT   BINDING         48
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00465,
FT                   ECO:0000269|PubMed:2123937"
FT   BINDING         78
FT                   /ligand="[2Fe-2S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:190135"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00465,
FT                   ECO:0000269|PubMed:2123937"
FT   STRAND          3..9
FT                   /evidence="ECO:0007829|PDB:3AV8"
FT   STRAND          14..20
FT                   /evidence="ECO:0007829|PDB:3AV8"
FT   HELIX           25..31
FT                   /evidence="ECO:0007829|PDB:3AV8"
FT   STRAND          42..46
FT                   /evidence="ECO:0007829|PDB:3AV8"
FT   STRAND          49..56
FT                   /evidence="ECO:0007829|PDB:3AV8"
FT   STRAND          61..63
FT                   /evidence="ECO:0007829|PDB:1FXI"
FT   HELIX           67..71
FT                   /evidence="ECO:0007829|PDB:3AV8"
FT   STRAND          74..76
FT                   /evidence="ECO:0007829|PDB:3AV8"
FT   HELIX           77..79
FT                   /evidence="ECO:0007829|PDB:3AV8"
FT   STRAND          84..89
FT                   /evidence="ECO:0007829|PDB:3AV8"
FT   HELIX           93..96
FT                   /evidence="ECO:0007829|PDB:3AV8"
SQ   SEQUENCE   97 AA;  10440 MW;  425B51114348F549 CRC64;
     MASYKVTLKT PDGDNVITVP DDEYILDVAE EEGLDLPYSC RAGACSTCAG KLVSGPAPDE
     DQSFLDDDQI QAGYILTCVA YPTGDCVIET HKEEALY