FER_ENTHI
ID FER_ENTHI Reviewed; 59 AA.
AC P11425;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1989, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Ferredoxin;
OS Entamoeba histolytica.
OC Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC Entamoeba.
OX NCBI_TaxID=5759;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=2903444; DOI=10.1016/0166-6851(88)90142-9;
RA Huber M., Garfinkel L., Gitler C., Mirelman D., Revel M., Rozenblatt S.;
RT "Nucleotide sequence analysis of an Entamoeba histolytica ferredoxin
RT gene.";
RL Mol. Biochem. Parasitol. 31:27-33(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] OF 1-8.
RC STRAIN=200:NIH;
RX PubMed=8719240; DOI=10.1016/0166-6851(95)02474-3;
RA Gilchrist C.A., Streets H.L., Ackers J.P., Hall R.;
RT "Transient expression of luciferase in Entamoeba histolytica driven by the
RT ferredoxin gene 5' and 3' regions.";
RL Mol. Biochem. Parasitol. 74:1-10(1995).
CC -!- FUNCTION: Ferredoxins are iron-sulfur proteins that transfer electrons
CC in a wide variety of metabolic reactions.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Note=Binds 2 [4Fe-4S] clusters.;
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DR EMBL; J03970; AAA29098.1; -; mRNA.
DR EMBL; L43139; AAC41611.1; -; Genomic_DNA.
DR PIR; A54516; A54516.
DR AlphaFoldDB; P11425; -.
DR SMR; P11425; -.
DR VEuPathDB; AmoebaDB:EHI5A_055540; -.
DR VEuPathDB; AmoebaDB:EHI_198670; -.
DR OMA; ACEENCP; -.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR Pfam; PF00037; Fer4; 2.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 4: Predicted;
KW 4Fe-4S; Electron transport; Iron; Iron-sulfur; Metal-binding; Repeat;
KW Transport.
FT CHAIN 1..59
FT /note="Ferredoxin"
FT /id="PRO_0000159160"
FT DOMAIN 2..30
FT /note="4Fe-4S ferredoxin-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT DOMAIN 31..59
FT /note="4Fe-4S ferredoxin-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT BINDING 12
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 15
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 18
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 22
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 41
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 44
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 47
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 51
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
SQ SEQUENCE 59 AA; 6052 MW; 1E78D5C062147CE9 CRC64;
MGKITIVNID DCVACGACSG TCPQSVLEVN DHVEIKNPDD CIGCGACVDA CPQGVLKVE
