FER_MYCSM
ID FER_MYCSM Reviewed; 106 AA.
AC P00215;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Ferredoxin;
GN Name=fdxA;
OS Mycolicibacterium smegmatis (Mycobacterium smegmatis).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1772;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=467663; DOI=10.1016/0014-5793(79)81332-0;
RA Hase T., Wakabayashi S., Matsubara H., Imai T., Matsumoto T., Tobari J.;
RT "Mycobacterium smegmatis ferredoxin: a unique distribution of cysteine
RT residues constructing iron-sulfur clusters.";
RL FEBS Lett. 103:224-228(1979).
CC -!- FUNCTION: Ferredoxins are iron-sulfur proteins that transfer electrons
CC in a wide variety of metabolic reactions.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Note=Binds 1 [4Fe-4S] cluster.;
CC -!- COFACTOR:
CC Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137;
CC Note=Binds 1 [3Fe-4S] cluster.;
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR PIR; A00219; FEMYFS.
DR PDB; 2V2K; X-ray; 1.60 A; A/B=1-105.
DR PDBsum; 2V2K; -.
DR AlphaFoldDB; P00215; -.
DR SMR; P00215; -.
DR STRING; 710686.Mycsm_04917; -.
DR eggNOG; COG1146; Bacteria.
DR OMA; GHEQWAG; -.
DR EvolutionaryTrace; P00215; -.
DR GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR000813; 7Fe_ferredoxin.
DR Pfam; PF00037; Fer4; 1.
DR PRINTS; PR00354; 7FE8SFRDOXIN.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; 3Fe-4S; 4Fe-4S; Direct protein sequencing;
KW Electron transport; Iron; Iron-sulfur; Metal-binding; Repeat; Transport.
FT CHAIN 1..106
FT /note="Ferredoxin"
FT /id="PRO_0000159101"
FT DOMAIN 30..59
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT REGION 81..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 8
FT /ligand="[3Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:21137"
FT /evidence="ECO:0000250"
FT BINDING 16
FT /ligand="[3Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:21137"
FT /evidence="ECO:0000250"
FT BINDING 20
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 39
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 42
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 45
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 49
FT /ligand="[3Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:21137"
FT /evidence="ECO:0000250"
FT STRAND 2..4
FT /evidence="ECO:0007829|PDB:2V2K"
FT HELIX 6..8
FT /evidence="ECO:0007829|PDB:2V2K"
FT TURN 9..11
FT /evidence="ECO:0007829|PDB:2V2K"
FT HELIX 15..19
FT /evidence="ECO:0007829|PDB:2V2K"
FT STRAND 25..27
FT /evidence="ECO:0007829|PDB:2V2K"
FT STRAND 32..34
FT /evidence="ECO:0007829|PDB:2V2K"
FT TURN 36..38
FT /evidence="ECO:0007829|PDB:2V2K"
FT HELIX 46..48
FT /evidence="ECO:0007829|PDB:2V2K"
FT STRAND 54..56
FT /evidence="ECO:0007829|PDB:2V2K"
FT HELIX 57..59
FT /evidence="ECO:0007829|PDB:2V2K"
FT HELIX 62..66
FT /evidence="ECO:0007829|PDB:2V2K"
FT HELIX 67..73
FT /evidence="ECO:0007829|PDB:2V2K"
FT TURN 74..78
FT /evidence="ECO:0007829|PDB:2V2K"
FT HELIX 84..87
FT /evidence="ECO:0007829|PDB:2V2K"
FT HELIX 95..98
FT /evidence="ECO:0007829|PDB:2V2K"
SQ SEQUENCE 106 AA; 11510 MW; F36C6C847FE067B1 CRC64;
TYVIAEPCVD VKDKACIEEC PVDCIYEGAR MLYIHPDECV DCGACEPVCP VEAIYYEDDV
PDQWSSYAQA NADFFAELGS PGGASKVGQT DNDPQAIKDL PPQGED
