FER_PYRAB
ID FER_PYRAB Reviewed; 67 AA.
AC Q9UXY2; G8ZK92;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Ferredoxin;
GN Name=fdxA; OrderedLocusNames=PYRAB17260; ORFNames=PAB7439;
OS Pyrococcus abyssi (strain GE5 / Orsay).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=272844;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GE5 / Orsay;
RX PubMed=12622808; DOI=10.1046/j.1365-2958.2003.03381.x;
RA Cohen G.N., Barbe V., Flament D., Galperin M., Heilig R., Lecompte O.,
RA Poch O., Prieur D., Querellou J., Ripp R., Thierry J.-C., Van der Oost J.,
RA Weissenbach J., Zivanovic Y., Forterre P.;
RT "An integrated analysis of the genome of the hyperthermophilic archaeon
RT Pyrococcus abyssi.";
RL Mol. Microbiol. 47:1495-1512(2003).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=GE5 / Orsay;
RX PubMed=22057919; DOI=10.1007/s00284-011-0035-x;
RA Gao J., Wang J.;
RT "Re-annotation of two hyperthermophilic archaea Pyrococcus abyssi GE5 and
RT Pyrococcus furiosus DSM 3638.";
RL Curr. Microbiol. 64:118-129(2012).
CC -!- FUNCTION: Ferredoxins are iron-sulfur proteins that transfer electrons
CC in a wide variety of metabolic reactions. {ECO:0000250}.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000250};
CC Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137; Evidence={ECO:0000250};
CC Note=Binds 1 [4Fe-4S] cluster which readily converts to a stable [3Fe-
CC 4S] form. {ECO:0000250};
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DR EMBL; AJ248288; CAB50631.1; -; Genomic_DNA.
DR EMBL; HE613800; CCE71199.1; -; Genomic_DNA.
DR PIR; A75024; A75024.
DR RefSeq; WP_010868845.1; NC_000868.1.
DR AlphaFoldDB; Q9UXY2; -.
DR SMR; Q9UXY2; -.
DR STRING; 272844.PAB7439; -.
DR EnsemblBacteria; CAB50631; CAB50631; PAB7439.
DR GeneID; 1496028; -.
DR KEGG; pab:PAB7439; -.
DR PATRIC; fig|272844.11.peg.1844; -.
DR eggNOG; arCOG00349; Archaea.
DR HOGENOM; CLU_139698_6_4_2; -.
DR OMA; DVFEMND; -.
DR OrthoDB; 111853at2157; -.
DR PhylomeDB; Q9UXY2; -.
DR Proteomes; UP000000810; Chromosome.
DR Proteomes; UP000009139; Chromosome.
DR GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR InterPro; IPR001080; 3Fe4S_ferredoxin.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR PRINTS; PR00352; 3FE4SFRDOXIN.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW 3Fe-4S; 4Fe-4S; Disulfide bond; Electron transport; Iron; Iron-sulfur;
KW Metal-binding; Repeat; Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..67
FT /note="Ferredoxin"
FT /id="PRO_0000159198"
FT DOMAIN 3..31
FT /note="4Fe-4S ferredoxin-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT DOMAIN 36..67
FT /note="4Fe-4S ferredoxin-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT BINDING 12
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 15
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 18
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 57
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT DISULFID 22..49
FT /evidence="ECO:0000250"
SQ SEQUENCE 67 AA; 7328 MW; AF9B062EBB5C4420 CRC64;
MAWKVSVDQD TCIGDAICAS LCPDVFEMND EGKAQPKVEI IEDEELYNCA KEAMESCPVS
AITIEEA
