FER_PYRIL
ID FER_PYRIL Reviewed; 107 AA.
AC P81901; A1RVR9;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 2.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Ferredoxin;
DE AltName: Full=Seven-iron ferredoxin;
GN OrderedLocusNames=Pisl_1904;
OS Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3).
OC Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Pyrobaculum.
OX NCBI_TaxID=384616;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4184 / JCM 9189 / GEO3;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T.,
RA Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Lowe T., Richardson P.;
RT "Complete sequence of Pyrobaculum islandicum DSM 4184.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP PROTEIN SEQUENCE OF 4-104, CHARACTERIZATION, AND MASS SPECTROMETRY.
RX PubMed=9538237; DOI=10.1093/oxfordjournals.jbchem.a021967;
RA Nakajima Y., Fujiwara T., Fukumori Y.;
RT "Purification and characterization of a [3Fe-4S][4Fe-4S] type ferredoxin
RT from hyperthermophilic archaeon, Pyrobaculum islandicum.";
RL J. Biochem. 123:521-527(1998).
CC -!- FUNCTION: Ferredoxins are iron-sulfur proteins that transfer electrons
CC in a wide variety of metabolic reactions.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Note=Binds 1 [4Fe-4S] cluster.;
CC -!- COFACTOR:
CC Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137;
CC Note=Binds 1 [3Fe-4S] cluster.;
CC -!- SUBUNIT: Monomer.
CC -!- PTM: The N-terminus is blocked.
CC -!- MASS SPECTROMETRY: Mass=11910; Mass_error=50; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:9538237};
CC -!- MISCELLANEOUS: Has a maximum absorption at about 282 nm.
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DR EMBL; CP000504; ABL89051.1; -; Genomic_DNA.
DR RefSeq; WP_011763626.1; NC_008701.1.
DR AlphaFoldDB; P81901; -.
DR SMR; P81901; -.
DR STRING; 384616.Pisl_1904; -.
DR EnsemblBacteria; ABL89051; ABL89051; Pisl_1904.
DR GeneID; 4616336; -.
DR KEGG; pis:Pisl_1904; -.
DR eggNOG; arCOG00291; Archaea.
DR HOGENOM; CLU_153636_0_0_2; -.
DR OMA; CPVKCIY; -.
DR OrthoDB; 98627at2157; -.
DR Proteomes; UP000002595; Chromosome.
DR GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProt.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR Pfam; PF13237; Fer4_10; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 1: Evidence at protein level;
KW 3Fe-4S; 4Fe-4S; Direct protein sequencing; Electron transport; Iron;
KW Iron-sulfur; Metal-binding; Repeat; Transport.
FT CHAIN 1..107
FT /note="Ferredoxin"
FT /id="PRO_0000159176"
FT DOMAIN 8..37
FT /note="4Fe-4S ferredoxin-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT DOMAIN 38..67
FT /note="4Fe-4S ferredoxin-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT BINDING 17
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 20
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 23
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT BINDING 27
FT /ligand="[3Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:21137"
FT /evidence="ECO:0000250"
FT BINDING 47
FT /ligand="[3Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:21137"
FT /evidence="ECO:0000250"
FT BINDING 53
FT /ligand="[3Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:21137"
FT /evidence="ECO:0000250"
FT BINDING 57
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /evidence="ECO:0000250"
FT CONFLICT 37
FT /note="N -> D (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 91
FT /note="K -> R (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 99
FT /note="K -> R (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 107 AA; 11882 MW; CDE5C9E96D164378 CRC64;
MAELAKYERV VIDQDICISC GACVAACPYQ ALELDENGKS RLIWEKCKDD FSCVAVCPVK
AISKASEATP EAKAKKGWYR FGKSLTPEEQ KAFEEWKTKY GITAPPV
