FER_THETR
ID FER_THETR Reviewed; 55 AA.
AC P00200; P00199;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Ferredoxin;
OS Thermoanaerobacterium thermosaccharolyticum (Clostridium
OS thermosaccharolyticum).
OC Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacterales Family III. Incertae Sedis; Thermoanaerobacterium.
OX NCBI_TaxID=1517;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=4768897; DOI=10.1016/s0021-9258(19)43591-6;
RA Tanaka M., Haniu M., Yasunobu K.T., Himes R.H., Akagi J.M.;
RT "The primary structure of the Clostridium thermosaccharolyticum ferredoxin,
RT a heat-stable ferredoxin.";
RL J. Biol. Chem. 248:5215-5217(1973).
RN [2]
RP PROTEIN SEQUENCE.
RC STRAIN=Tartarivorum;
RX PubMed=4934841; DOI=10.1016/s0021-9258(18)62126-x;
RA Tanaka M., Haniu M., Matsueda G., Yasunobu K.T., Himes R.H., Akagi J.M.,
RA Barnes E.M., Devanathan T.;
RT "The primary structure of the Clostridium tartarivorum ferredoxin, a heat-
RT stable ferredoxin.";
RL J. Biol. Chem. 246:3953-3960(1971).
CC -!- FUNCTION: Ferredoxins are iron-sulfur proteins that transfer electrons
CC in a wide variety of metabolic reactions.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Note=Binds 2 [4Fe-4S] clusters.;
CC -!- CAUTION: PubMed:4934841 authors considered 'C.tartarivorum' as a
CC separate species. {ECO:0000305}.
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DR PIR; A92138; FECLCT.
DR AlphaFoldDB; P00200; -.
DR SMR; P00200; -.
DR OMA; PAECIVQ; -.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR000813; 7Fe_ferredoxin.
DR Pfam; PF12838; Fer4_7; 1.
DR PRINTS; PR00354; 7FE8SFRDOXIN.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 1: Evidence at protein level;
KW 4Fe-4S; Direct protein sequencing; Electron transport; Iron; Iron-sulfur;
KW Metal-binding; Repeat; Transport.
FT CHAIN 1..55
FT /note="Ferredoxin"
FT /id="PRO_0000159116"
FT DOMAIN 2..27
FT /note="4Fe-4S ferredoxin-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT DOMAIN 28..55
FT /note="4Fe-4S ferredoxin-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT BINDING 8
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 11
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 14
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 18
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 37
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 40
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 43
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 47
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT CONFLICT 31
FT /note="E -> Q (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 44
FT /note="E -> Q (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 55 AA; 5545 MW; 7C965887CC64E53C CRC64;
AHIITDECIS CGACAAECPV EAIHEGTGKY EVDADTCIDC GACEAVCPTG AVKAE
