ID   FES1_PHANO              Reviewed;         211 AA.
AC   Q0V4C4;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Hsp70 nucleotide exchange factor FES1;
GN   Name=FES1; ORFNames=SNOG_01140;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS   blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC   Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT   analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- FUNCTION: Functions as a nucleotide exchange factor (NEF) for Hsp70
CC       chaperones which accelerates the release of ADP. Required for fully
CC       efficient Hsp70-mediated folding of proteins (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FES1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH445326; EAT90789.1; -; Genomic_DNA.
DR   RefSeq; XP_001791795.1; XM_001791743.1.
DR   AlphaFoldDB; Q0V4C4; -.
DR   SMR; Q0V4C4; -.
DR   STRING; 13684.SNOT_01140; -.
DR   EnsemblFungi; SNOT_01140; SNOT_01140; SNOG_01140.
DR   GeneID; 5968640; -.
DR   KEGG; pno:SNOG_01140; -.
DR   eggNOG; KOG2160; Eukaryota.
DR   HOGENOM; CLU_084507_0_0_1; -.
DR   InParanoid; Q0V4C4; -.
DR   OMA; MEPLGLW; -.
DR   OrthoDB; 1310125at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000774; F:adenyl-nucleotide exchange factor activity; IBA:GO_Central.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR013918; Nucleotide_exch_fac_Fes1.
DR   Pfam; PF08609; Fes1; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Repeat; Translation regulation.
FT   CHAIN           1..211
FT                   /note="Hsp70 nucleotide exchange factor FES1"
FT                   /id="PRO_0000285399"
FT   REPEAT          27..67
FT                   /note="ARM 1"
FT   REPEAT          86..125
FT                   /note="ARM 2"
FT   REPEAT          129..169
FT                   /note="ARM 3"
FT   REGION          12..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   211 AA;  23334 MW;  F877D2B14A839DDE CRC64;
     MNDPQLNNLL KWGIQNSDAS RNDPSTAPQP LSEVDKEALQ QLIAGVRGPS DADLMQDSFQ
     VIENNEATAE AKHQAFENFE QLIQGIDNAN NMEALGLWTK LIKQLESEDP VIRKWAAWCC
     STAVQNNVRS QERLLVLKNA IPTLVRLATS DPDKTARKKA TSALSSAVRN FQPGLDAVLE
     HMPAEHKPKE ALDANDMASV DILINKLRES I