FETA_BOSIN
ID FETA_BOSIN Reviewed; 11 AA.
AC P83128;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 07-APR-2021, entry version 35.
DE RecName: Full=Probable alpha-fetoprotein;
DE AltName: Full=Alpha-1-fetoprotein;
DE AltName: Full=Alpha-fetoglobulin;
DE Flags: Fragment;
GN Name=AFP;
OS Bos indicus (Zebu).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9915;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, TISSUE SPECIFICITY, AND GLYCOSYLATION.
RC TISSUE=Fetal cotyledon {ECO:0000269|PubMed:12405451};
RX PubMed=12405451; DOI=10.1051/rnd:2002021;
RA Sousa N.M., Remy B., El Amiri B., De Figueiredo J.R., Banga-Mboko H.,
RA Dias Goncalves P.B., Beckers J.-F.M.P.;
RT "Characterization of pregnancy-associated glycoproteins extracted from zebu
RT (Bos indicus) placentas removed at different gestational periods.";
RL Reprod. Nutr. Dev. 42:227-241(2002).
CC -!- FUNCTION: Binds copper, nickel, and fatty acids as well as, and
CC bilirubin less well than, serum albumin. {ECO:0000250}.
CC -!- SUBUNIT: Dimeric and trimeric forms have been found in addition to the
CC monomeric form. {ECO:0000250|UniProtKB:P02771}.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Placenta. {ECO:0000269|PubMed:12405451}.
CC -!- PTM: Glycosylated. {ECO:0000269|PubMed:12405451}.
CC -!- SIMILARITY: Belongs to the ALB/AFP/VDB family. {ECO:0000255|PROSITE-
CC ProRule:PRU00769}.
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DR Proteomes; UP000515132; Genome assembly.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Copper; Direct protein sequencing; Glycoprotein; Metal-binding; Nickel;
KW Reference proteome; Secreted.
FT CHAIN 1..>11
FT /note="Probable alpha-fetoprotein"
FT /id="PRO_0000262969"
FT DOMAIN 1..>11
FT /note="Albumin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00769"
FT NON_TER 11
FT /evidence="ECO:0000303|PubMed:12405451"
SQ SEQUENCE 11 AA; 1234 MW; CE8EA47EA0586B5D CRC64;
DKNAYGIDLI L