FGFP2_CHICK
ID FGFP2_CHICK Reviewed; 208 AA.
AC Q802A9;
DT 11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Fibroblast growth factor-binding protein 2;
DE Short=FGF-BP2;
DE Short=FGF-binding protein 2;
DE Short=FGFBP-2;
DE Flags: Precursor;
GN Name=FGFBP2;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA McDonnell K., Wellstein A.;
RT "A chicken fibroblast growth factor binding protein in embryo development
RT revealed by RNA interference.";
RL Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the fibroblast growth factor-binding protein
CC family. {ECO:0000305}.
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DR EMBL; AY164487; AAO23116.1; -; mRNA.
DR RefSeq; NP_989778.1; NM_204447.1.
DR AlphaFoldDB; Q802A9; -.
DR DIP; DIP-58560N; -.
DR IntAct; Q802A9; 1.
DR STRING; 9031.ENSGALP00000023367; -.
DR PaxDb; Q802A9; -.
DR PRIDE; Q802A9; -.
DR Ensembl; ENSGALT00000023412; ENSGALP00000023367; ENSGALG00000014501.
DR GeneID; 395094; -.
DR KEGG; gga:395094; -.
DR CTD; 83888; -.
DR VEuPathDB; HostDB:geneid_395094; -.
DR eggNOG; ENOG502S0EZ; Eukaryota.
DR GeneTree; ENSGT00940000154372; -.
DR HOGENOM; CLU_086542_0_0_1; -.
DR InParanoid; Q802A9; -.
DR OMA; CEYRGQP; -.
DR OrthoDB; 1528446at2759; -.
DR PhylomeDB; Q802A9; -.
DR TreeFam; TF335877; -.
DR PRO; PR:Q802A9; -.
DR Proteomes; UP000000539; Chromosome 4.
DR Bgee; ENSGALG00000014501; Expressed in cerebellum and 6 other tissues.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR GO; GO:0019838; F:growth factor binding; IBA:GO_Central.
DR GO; GO:0007267; P:cell-cell signaling; IBA:GO_Central.
DR InterPro; IPR010510; FGF1-bd.
DR PANTHER; PTHR15258; PTHR15258; 1.
DR Pfam; PF06473; FGF-BP1; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Growth factor binding; Reference proteome; Secreted;
KW Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..208
FT /note="Fibroblast growth factor-binding protein 2"
FT /id="PRO_0000245861"
FT REGION 130..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 43..59
FT /evidence="ECO:0000250"
FT DISULFID 68..102
FT /evidence="ECO:0000250"
FT DISULFID 77..113
FT /evidence="ECO:0000250"
FT DISULFID 191..199
FT /evidence="ECO:0000250"
SQ SEQUENCE 208 AA; 23261 MW; 87BE487863333C77 CRC64;
MKRVALLFLV VICGMGGLGQ KLKPKKRSNG EEINFRTKTK DVCTMRISGD EEMKARIECK
GQGKSYWCEY TGMPLLCHPF QNNPKMYWNQ ITMELRKLPH ACESTQMLKA SMCQKAPVDA
LMKQVAAGVE PEDGANRDKS SQKTSASVRG AGKSSVKKTG KPAVLPRIKP TQHGQGSENE
TEAMKLAREH CWESLHEFCS YIIGFFRG