FGOP2_DANRE
ID FGOP2_DANRE Reviewed; 215 AA.
AC Q7T338;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=FGFR1 oncogene partner 2 homolog;
GN Name=fgfr1op2; ORFNames=si:ch211-203h15.2, zgc:64126;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the SIKE family. {ECO:0000305}.
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DR EMBL; CR847994; CAK04410.1; -; Genomic_DNA.
DR EMBL; BC053266; AAH53266.1; -; mRNA.
DR RefSeq; NP_956249.1; NM_199955.1.
DR AlphaFoldDB; Q7T338; -.
DR SMR; Q7T338; -.
DR STRING; 7955.ENSDARP00000005747; -.
DR PaxDb; Q7T338; -.
DR Ensembl; ENSDART00000021139; ENSDARP00000005747; ENSDARG00000009657.
DR GeneID; 335511; -.
DR KEGG; dre:335511; -.
DR CTD; 26127; -.
DR ZFIN; ZDB-GENE-030131-7451; fgfr1op2.
DR eggNOG; ENOG502QSAD; Eukaryota.
DR GeneTree; ENSGT00390000018003; -.
DR HOGENOM; CLU_073167_1_0_1; -.
DR InParanoid; Q7T338; -.
DR OMA; DHENTAD; -.
DR OrthoDB; 1368908at2759; -.
DR PhylomeDB; Q7T338; -.
DR TreeFam; TF324337; -.
DR PRO; PR:Q7T338; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 4.
DR Bgee; ENSDARG00000009657; Expressed in granulocyte and 27 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009611; P:response to wounding; IBA:GO_Central.
DR InterPro; IPR008555; SIKE.
DR PANTHER; PTHR12186; PTHR12186; 2.
DR Pfam; PF05769; SIKE; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Cytoplasm; Reference proteome.
FT CHAIN 1..215
FT /note="FGFR1 oncogene partner 2 homolog"
FT /id="PRO_0000299046"
FT COILED 35..183
FT /evidence="ECO:0000255"
SQ SEQUENCE 215 AA; 25007 MW; 6DEB9F4F2FD62A63 CRC64;
MTCTLEKVLA DAKSLVERLR DHDSAAEILI EQTTLLNKRV EAMKQYQEEI EVLNQVARHR
PRSTLVMGIQ QENRQIRELQ QENKELHTSL EEHQSALELI MSKYREQVFR LLMASKKEDP
TIVTQLREQH TNEMQAHIEK INEMATVMRK AIEVDEGRLC EDEERIKRLE LENSGLRELL
GISREAFLLL KRDDTSDSTS LSPLLTSTDI SLRKS