ID   FH12_ARATH              Reviewed;         299 AA.
AC   Q9C7S1;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 2.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Formin-like protein 12;
DE            Short=AtFH12;
GN   Name=FH12; OrderedLocusNames=At1g42980; ORFNames=F13A11.4;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX   PubMed=12417149; DOI=10.1016/s1360-1385(02)02341-5;
RA   Deeks M.J., Hussey P.J., Davies B.;
RT   "Formins: intermediates in signal-transduction cascades that affect
RT   cytoskeletal reorganization.";
RL   Trends Plant Sci. 7:492-498(2002).
RN   [4]
RP   GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX   PubMed=15256004; DOI=10.1186/1471-2164-5-44;
RA   Cvrckova F., Novotny M., Pickova D., Zarsky V.;
RT   "Formin homology 2 domains occur in multiple contexts in angiosperms.";
RL   BMC Genomics 5:44-44(2004).
CC   -!- SIMILARITY: Belongs to the formin-like family. Class-II subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG51518.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC068324; AAG51518.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE31934.1; -; Genomic_DNA.
DR   PIR; D96497; D96497.
DR   RefSeq; NP_174997.2; NM_103457.3.
DR   AlphaFoldDB; Q9C7S1; -.
DR   SMR; Q9C7S1; -.
DR   STRING; 3702.AT1G42980.1; -.
DR   iPTMnet; Q9C7S1; -.
DR   PaxDb; Q9C7S1; -.
DR   PRIDE; Q9C7S1; -.
DR   EnsemblPlants; AT1G42980.1; AT1G42980.1; AT1G42980.
DR   GeneID; 840896; -.
DR   Gramene; AT1G42980.1; AT1G42980.1; AT1G42980.
DR   KEGG; ath:AT1G42980; -.
DR   Araport; AT1G42980; -.
DR   TAIR; locus:2009869; AT1G42980.
DR   eggNOG; KOG1922; Eukaryota.
DR   HOGENOM; CLU_028505_0_0_1; -.
DR   InParanoid; Q9C7S1; -.
DR   OrthoDB; 263102at2759; -.
DR   PhylomeDB; Q9C7S1; -.
DR   PRO; PR:Q9C7S1; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9C7S1; baseline and differential.
DR   Genevisible; Q9C7S1; AT.
DR   GO; GO:0003779; F:actin binding; ISS:TAIR.
DR   Gene3D; 1.20.58.2220; -; 1.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   Pfam; PF02181; FH2; 1.
DR   PROSITE; PS51444; FH2; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..299
FT                   /note="Formin-like protein 12"
FT                   /id="PRO_0000308537"
FT   DOMAIN          1..295
FT                   /note="FH2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00774"
SQ   SEQUENCE   299 AA;  34169 MW;  062FC5E1F40FB262 CRC64;
     MASNCEKMLS KIKIPLPDML NAVLDLDSSA VIIDQIKNLI KICWSKEEMD RLRNSAGGDK
     EVLGKCEEIF GELMMVPRIE PKLRVFAFKV EYPSRVSDLK MWMHTIIAAT KEITGSVKLF
     RIMQTSLTMQ VLRGSNVECG LDSLVKLCDN VYLMHDFCKL LDFGNDLVHL EAASRIELET
     ITNKMQELFD IEEEVNDEFL ASENDGANFV GYRNVVHDFL CTIDGDKQLL NILYAEVGGL
     VNSYIAEYPS GVRFKEATNI LTRFVETFYK SREEIERQAE AEKEILEKRK MNIKQNGNL