FH15A_ARATH
ID FH15A_ARATH Reviewed; 405 AA.
AC P0C5K2; F4K838; Q9FLR6;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Formin-like protein 15a;
DE Short=AtFH15a;
GN Name=FH15A; OrderedLocusNames=At5g07650; ORFNames=MBK20.9;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=12417149; DOI=10.1016/s1360-1385(02)02341-5;
RA Deeks M.J., Hussey P.J., Davies B.;
RT "Formins: intermediates in signal-transduction cascades that affect
RT cytoskeletal reorganization.";
RL Trends Plant Sci. 7:492-498(2002).
RN [4]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=15256004; DOI=10.1186/1471-2164-5-44;
RA Cvrckova F., Novotny M., Pickova D., Zarsky V.;
RT "Formin homology 2 domains occur in multiple contexts in angiosperms.";
RL BMC Genomics 5:44-44(2004).
CC -!- SIMILARITY: Belongs to the formin-like family. Class-II subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AED91189.1; Type=Erroneous gene model prediction; Note=The predicted gene At5g07650 has been split into 2 genes: At5g07645 and At5g07650.; Evidence={ECO:0000305};
CC Sequence=BAB11443.1; Type=Erroneous gene model prediction; Note=The predicted gene At5g07650 has been split into 2 genes: At5g07645 and At5g07650.; Evidence={ECO:0000305};
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DR EMBL; AB010070; BAB11443.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED91189.1; ALT_SEQ; Genomic_DNA.
DR AlphaFoldDB; P0C5K2; -.
DR SMR; P0C5K2; -.
DR PeptideAtlas; P0C5K2; -.
DR PRIDE; P0C5K2; -.
DR Araport; AT5G07650; -.
DR HOGENOM; CLU_366986_0_0_1; -.
DR InParanoid; P0C5K2; -.
DR PRO; PR:P0C5K2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; P0C5K2; baseline and differential.
DR Gene3D; 1.20.58.2220; -; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR Pfam; PF02181; FH2; 2.
DR SMART; SM00498; FH2; 1.
DR PROSITE; PS51444; FH2; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..405
FT /note="Formin-like protein 15a"
FT /id="PRO_0000308540"
FT DOMAIN 52..405
FT /note="FH2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00774"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..31
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 45972 MW; D9AC87E11F18433A CRC64;
MSLVEISGSD AMAAPMPGRV PPPPPRPPPM PRRLPPMFDA FDHTGAGMVW GFPRPAKKRA
SLKPLHWVKI TSDLQGSLWD ELQRRHGDSQ TAIELDISEL ETLFFVEAKP EKIRLHDLRR
ASYRVFNVIN LSMPLPDMMT AVLAMDESVV DVDQIEKLIK FCPTNEEMEL LKTYTGDKAA
LGKYEQYLLE LMKVPRLEAK LRVFSFKTQF GTKITELKER LNVVTSACEE NLLLIHQVRS
SEKLKEIMKK IPCLGNTSNQ GPDRGKTFLS PVEFKLDRLS VKRMHYFCKL KEIMKKIPCL
GNTSKSNPRV GVKLDSSVSD THTVKSMHYY CKVLASEASE LLDVYKDLQS LESASKIQVK
SLAQNIQAII KRLEKLKQEL TASETDGPAS EVFCNVCWFF VRLMI