FH15_ORYSJ
ID FH15_ORYSJ Reviewed; 788 AA.
AC Q69MT2; B7ESA3;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2004, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Formin-like protein 15;
DE AltName: Full=OsFH15;
DE Flags: Precursor;
GN Name=FH15; OrderedLocusNames=Os09g0517600, LOC_Os09g34180;
GN ORFNames=OSJNBb0034B12.29;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15256004; DOI=10.1186/1471-2164-5-44;
RA Cvrckova F., Novotny M., Pickova D., Zarsky V.;
RT "Formin homology 2 domains occur in multiple contexts in angiosperms.";
RL BMC Genomics 5:44-44(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000305}.
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DR EMBL; AP005735; BAD33833.1; -; Genomic_DNA.
DR EMBL; AP008215; BAF25594.1; -; Genomic_DNA.
DR EMBL; AP014965; BAT08977.1; -; Genomic_DNA.
DR EMBL; AK101828; BAG95250.1; -; mRNA.
DR RefSeq; XP_015612411.1; XM_015756925.1.
DR AlphaFoldDB; Q69MT2; -.
DR SMR; Q69MT2; -.
DR STRING; 4530.OS09T0517600-01; -.
DR PaxDb; Q69MT2; -.
DR PRIDE; Q69MT2; -.
DR EnsemblPlants; Os09t0517600-01; Os09t0517600-01; Os09g0517600.
DR GeneID; 4347588; -.
DR Gramene; Os09t0517600-01; Os09t0517600-01; Os09g0517600.
DR KEGG; osa:4347588; -.
DR eggNOG; KOG1922; Eukaryota.
DR HOGENOM; CLU_007699_0_2_1; -.
DR InParanoid; Q69MT2; -.
DR OMA; ANAACCN; -.
DR OrthoDB; 1204639at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR Genevisible; Q69MT2; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; -; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213; PTHR23213; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR PROSITE; PS51444; FH2; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..18
FT /evidence="ECO:0000255"
FT CHAIN 19..788
FT /note="Formin-like protein 15"
FT /id="PRO_0000319005"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 340..768
FT /note="FH2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00774"
FT REGION 48..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 193..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..85
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..281
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..347
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 788 AA; 84580 MW; 3DEDDD6E94700CA8 CRC64;
MLARWLLVLL LLLPVSWCHQ DRHGRRHYPR RWRSSGSRRE LHEPLFPLEN APALPPPPPP
PPAPFFPFLP DSAPPQLPPP VTTPAPAGGA GDGGTDAGAA ATGDASSSSS SSASPHPTAP
ANISYMAMPI YHSAPLRSFL SSHRLLTVLL PVAAVLAAVL AAALVYLLTR RRRCSKGEPH
AAHTKAVLLS PGNSTALYDG DHDQHGRGST ATAASSASSP ELRPMPPLPR QFQQTRTSMP
STSQTIHEAG AEDKRAPPPQ SVRPPPPPPP PPPPPPMPPR TDNASTQAAP APPPPLPRAG
NGSGWLPRRY TERAAPTVIR ASAGAVHPEE SPARASPEEK AADAAARPKL KPLHWDKVRP
ASSGRPTVWD QLKASSFRVN EEMIETLFVS NSTRRASKNG VKEANAACCN QENKVLDPKK
SQNIAIMLRA LDATKEEVCK ALLDGQAESL GTELLETLLK MAPSREEEIK LKEFREDAVS
KLGPAESFLK AVLAIPFAFK RVEAMLYIAN FDSEVDYLKT SFKTLEAACE ELRGSRLFHK
ILDAVLKTGN RMNTGTNRGN ASAFKLDALL KLVDVKGADG KTTLLHFVIE EIVKSEGASI
LATGQTSNQG SAIADDFQCK KVGLRIVASL GGELGNVKKA AGMDSDTLAS CVAKLSAGVS
KISEALQLNQ QLGSDDHCKR FRASIGEFLQ KAEAEITAVQ AQESLALSLV RETTEFFHGD
SVKEEGHPLR IFMVVRDFLT VLDHVCKDVG RMNERTAIGS SLRLENAPVL ARFNAVQPSS
SEEESSSS
