FH16_ARATH
ID FH16_ARATH Reviewed; 722 AA.
AC Q9FF15;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 2.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Formin-like protein 16;
DE Short=AtFH16;
GN Name=FH16; OrderedLocusNames=At5g07770; ORFNames=MBK20.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT features of the 1.6 Mb regions covered by twenty physically assigned P1
RT clones.";
RL DNA Res. 4:215-230(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT features of the regions of 1,456,315 bp covered by nineteen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:41-54(1998).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=12417149; DOI=10.1016/s1360-1385(02)02341-5;
RA Deeks M.J., Hussey P.J., Davies B.;
RT "Formins: intermediates in signal-transduction cascades that affect
RT cytoskeletal reorganization.";
RL Trends Plant Sci. 7:492-498(2002).
RN [5]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=15256004; DOI=10.1186/1471-2164-5-44;
RA Cvrckova F., Novotny M., Pickova D., Zarsky V.;
RT "Formin homology 2 domains occur in multiple contexts in angiosperms.";
RL BMC Genomics 5:44-44(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9FF15-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the formin-like family. Class-II subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB09941.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB005249; BAB09941.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AB010070; BAB09941.1; JOINED; Genomic_DNA.
DR EMBL; CP002688; AED91201.1; -; Genomic_DNA.
DR RefSeq; NP_196394.2; NM_120859.3. [Q9FF15-1]
DR AlphaFoldDB; Q9FF15; -.
DR SMR; Q9FF15; -.
DR STRING; 3702.AT5G07770.1; -.
DR iPTMnet; Q9FF15; -.
DR PaxDb; Q9FF15; -.
DR PRIDE; Q9FF15; -.
DR EnsemblPlants; AT5G07770.1; AT5G07770.1; AT5G07770. [Q9FF15-1]
DR GeneID; 830670; -.
DR Gramene; AT5G07770.1; AT5G07770.1; AT5G07770. [Q9FF15-1]
DR KEGG; ath:AT5G07770; -.
DR Araport; AT5G07770; -.
DR TAIR; locus:2160329; AT5G07770.
DR eggNOG; KOG1922; Eukaryota.
DR InParanoid; Q9FF15; -.
DR PhylomeDB; Q9FF15; -.
DR PRO; PR:Q9FF15; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FF15; baseline and differential.
DR Genevisible; Q9FF15; AT.
DR GO; GO:0003779; F:actin binding; ISS:TAIR.
DR Gene3D; 1.20.58.2220; -; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..722
FT /note="Formin-like protein 16"
FT /id="PRO_0000308542"
FT DOMAIN 182..571
FT /note="FH2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00774"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 635..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..56
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..663
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..722
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 722 AA; 79235 MW; 2B8CF33ABABCA5DB CRC64;
MSPVEITGAD AVVTPPMRGR VPLPPPPPPP MRRSAPSPPP MSGRVPPPPP PPPMFDPKGA
GRVICCLRPG QNKSSLKRFQ CGKLTNAWEE LQRHGEAQTA PEFDLSEIEA LFSAAVQNQA
DKSGSRREAF EANPDKLQLI SGADALVPLP PPPPPMPRRS PPPPPPRFDA FDHKGARMVC
GFRCPVTKRS SLKPLHWVKI TRALQGSLWD ELQIQYGESQ TAIELDVPEI ETLFSVGAKP
RPKPKPEKVP LIDLKRANNT IVNLKILKMP LPDMMAAVMA MDESVLDVDQ IENLIQLCPT
KEEMELLKNY TGDKATLGKS EQCLLELMKV PRFEAKLRVL SFKIPFGTKI TKFRKMLNVV
NSACEEVRSS QMLKEIMKII LFLGNTLNQG TARGSAVGFR LDSLLILSET RADNNKMTLM
HYLCKVLASK AADLLDFHKD LQSLESTLEI NLKSLAEEIH AITKGLEKLK QELTASETDG
PVSQVFRKLL KDFISSAETQ VATVSTLYSS ARINADALAH YFGEDPNHYP FEKVSATLLS
FIRLFKKAHQ ENVKQEDLEK KKAATEDVFG GPDHNIDSDT SLDDSEAKSP SRIRPPPSIP
RPPSRPRYAC CRIPAVNPPP RLVCGPYPLP RLVRVGSPSP PPPSMSGGAP PPPPPPPMLV
ASRTAPPPHL SHVRSIPFQT RLVMGTSPLP LLVREGAPPP TLPSMSGGAP PPPPPLPMLR
YQ
