FH16_ORYSJ
ID FH16_ORYSJ Reviewed; 906 AA.
AC A3AB67; Q0DXQ8;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Formin-like protein 16;
DE AltName: Full=OsFH16;
DE Flags: Precursor;
GN Name=FH16; OrderedLocusNames=Os02g0739100, LOC_Os02g50570;
GN ORFNames=OsJ_008039;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15256004; DOI=10.1186/1471-2164-5-44;
RA Cvrckova F., Novotny M., Pickova D., Zarsky V.;
RT "Formin homology 2 domains occur in multiple contexts in angiosperms.";
RL BMC Genomics 5:44-44(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AK072070; Type=Miscellaneous discrepancy; Note=Probable cloning artifact leading to an internal deletion.; Evidence={ECO:0000305};
CC Sequence=BAF09980.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP008208; BAF09980.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000139; EAZ24556.1; -; Genomic_DNA.
DR EMBL; AK072070; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015625870.1; XM_015770384.1.
DR AlphaFoldDB; A3AB67; -.
DR SMR; A3AB67; -.
DR STRING; 4530.OS02T0739100-01; -.
DR iPTMnet; A3AB67; -.
DR PaxDb; A3AB67; -.
DR PRIDE; A3AB67; -.
DR GeneID; 4330671; -.
DR KEGG; osa:4330671; -.
DR eggNOG; KOG1922; Eukaryota.
DR InParanoid; A3AB67; -.
DR OrthoDB; 1204639at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000007752; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; -; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213; PTHR23213; 2.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR PROSITE; PS51444; FH2; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..906
FT /note="Formin-like protein 16"
FT /id="PRO_0000319006"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 396..849
FT /note="FH2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00774"
FT REGION 34..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 834..906
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..65
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..213
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..296
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..389
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..474
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 829
FT /note="D -> V (in Ref. 5; AK072070)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 906 AA; 95565 MW; 4B8C42468848A2EC CRC64;
MAPAPSPTPL PLFLLLLLLV GVAPLAAAQG QNIQTRFPST RTPAFATPPP ITSPSPSPGT
PTATPSSSPP SSSGKRSDIA VAVVSTALSS FAVSGLAFFL FLRHGKKREL TEAGGAGQHY
GGAQGGALTG KRPEREPKRP ARGNMVDENG LDAIYWREFE KEGDGGRGRK PPASRRPPQP
PPPRPYRAER RQDAHESSAP SPPRSRKNRI DQEPLIPRGS LDSASAEFDE SLYAPSAGST
SSFSVAAAEA YARPPSTPAI TAVSSVPRSS PSPAPAPAAR PASPSPSLPL PPGRESPSRP
QSIAAAAVAS PAPPPPPPPK PAAAAPPPPP PPKAAPPPPP PKGPPPPPPA KGPPPPPPPK
GPSPPPPPPP GGKKGGPPPP PPKGGASRPP AAPGVPTGSA DQQAKLKPLH WDKVNVAATD
HSMVWDNITG GSFNLDEGII EALFGTAAVN RKTKPADSKD ASGGSTSAGL GRSNSPEQIF
LLEPRKSHNI SIILRSLTVG REEIIDALLN GHTELSTEVL EKLSRLNISK EEENTLLKFS
GNPDRLAPAE FFLLRLLLDV PSPFARVNAL LFKANYAAEV AQLKQSLRTL EMASQELRTK
GLFFKLLEAV LKAGNRMNAG TARGNAQAFN LTALRKLSDV KSTDGSTTLL HFVIEEVVRS
EGKRLAINRN YSLRRSGSLA KSTDGGNPAA SSTSQGPSRE ERQNEYLNLG LPIVGGLSTE
FANVKKAALV DYDTVVNECA ILGNRLAGTK KLLETYGDDG FARGLRGFVK AAEQELNELK
GNQEKVLELV QRTTEYYHTG ATKDKNAHPL QLFIIVRDFL GMVDQACVDI KRKLQQQKKP
TPPPSSSQPA APAATTKGAA DDAPAPAQKP PEEVDSKRKR VMPRFPNLPA HFMKDNADSD
SSSDEE
