ID   FH19_ARATH              Reviewed;         464 AA.
AC   Q9FF14;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Formin-like protein 19;
DE            Short=AtFH19;
GN   Name=FH19; OrderedLocusNames=At5g07780; ORFNames=MXM12.2;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9330910; DOI=10.1093/dnares/4.3.215;
RA   Sato S., Kotani H., Nakamura Y., Kaneko T., Asamizu E., Fukami M.,
RA   Miyajima N., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. I. Sequence
RT   features of the 1.6 Mb regions covered by twenty physically assigned P1
RT   clones.";
RL   DNA Res. 4:215-230(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX   PubMed=12417149; DOI=10.1016/s1360-1385(02)02341-5;
RA   Deeks M.J., Hussey P.J., Davies B.;
RT   "Formins: intermediates in signal-transduction cascades that affect
RT   cytoskeletal reorganization.";
RL   Trends Plant Sci. 7:492-498(2002).
RN   [5]
RP   GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX   PubMed=15256004; DOI=10.1186/1471-2164-5-44;
RA   Cvrckova F., Novotny M., Pickova D., Zarsky V.;
RT   "Formin homology 2 domains occur in multiple contexts in angiosperms.";
RL   BMC Genomics 5:44-44(2004).
CC   -!- SIMILARITY: Belongs to the formin-like family. Class-II subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB005249; BAB09942.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED91203.1; -; Genomic_DNA.
DR   EMBL; AK221526; BAD94830.1; -; mRNA.
DR   RefSeq; NP_196395.1; NM_120860.3.
DR   AlphaFoldDB; Q9FF14; -.
DR   SMR; Q9FF14; -.
DR   STRING; 3702.AT5G07780.1; -.
DR   PaxDb; Q9FF14; -.
DR   PRIDE; Q9FF14; -.
DR   EnsemblPlants; AT5G07780.1; AT5G07780.1; AT5G07780.
DR   GeneID; 830671; -.
DR   Gramene; AT5G07780.1; AT5G07780.1; AT5G07780.
DR   KEGG; ath:AT5G07780; -.
DR   Araport; AT5G07780; -.
DR   TAIR; locus:2177801; AT5G07780.
DR   eggNOG; KOG1922; Eukaryota.
DR   HOGENOM; CLU_028505_0_0_1; -.
DR   InParanoid; Q9FF14; -.
DR   OMA; SNMTLMH; -.
DR   OrthoDB; 1204639at2759; -.
DR   PhylomeDB; Q9FF14; -.
DR   PRO; PR:Q9FF14; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FF14; baseline and differential.
DR   Genevisible; Q9FF14; AT.
DR   GO; GO:0003779; F:actin binding; ISS:TAIR.
DR   GO; GO:0045010; P:actin nucleation; IDA:TAIR.
DR   GO; GO:0051016; P:barbed-end actin filament capping; IDA:TAIR.
DR   Gene3D; 1.20.58.2220; -; 1.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM00498; FH2; 1.
DR   PROSITE; PS51444; FH2; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..464
FT                   /note="Formin-like protein 19"
FT                   /id="PRO_0000308545"
FT   DOMAIN          68..462
FT                   /note="FH2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00774"
FT   REGION          1..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..70
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   464 AA;  52410 MW;  0673BFFCA89AEB3B CRC64;
     MSLVDISGAY SLVPLPPPPP PLMRRRAPLP PPPPPPLMRR RAPPPPPPPL MRRRAPPPPP
     PPPLPRPCSR PPKTKCSLKP LHWVKKTRAL PGSLWDELQR RQECRDIEDE QILCAIELSV
     SEIETIFSLG AKPKPKPEPE KVPLIDLRRA TNTEIRLMLL NIRLPDMIAA AMAMDESRLD
     DFDQIENLIN LFPTKEDMKF LLTYTGDKGN CEQLFQYLQE VVKVPRVESK LRVFSFKIQF
     GTQITKLTKG LNAVNSACEE IRTSQKLKDI MENILCLGNI LNQGTGRGRA VGFRLDSLLI
     LSETRADNSK MTLMHYLCKV LASKASDLLD FHKDLESLES ASKIQLKSLA EEIQAITKGL
     EKLKQELTAS ETDGPVSQVF RKLLKEFISN AETQVATVMA LYYPARGNAE ALAHYFGYHY
     PFEQVTATLL SFIRLFKKAH EENVKQAELE KKKAAKEAEM EKTK