FH1_ORYSJ
ID FH1_ORYSJ Reviewed; 960 AA.
AC Q8S0F0; Q0JGX4;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Formin-like protein 1;
DE AltName: Full=OsFH1;
DE Flags: Precursor;
GN Name=FH1; OrderedLocusNames=Os01g0897700, LOC_Os01g67240;
GN ORFNames=P0506A10.7, P0674H09.24;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 717-960.
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15256004; DOI=10.1186/1471-2164-5-44;
RA Cvrckova F., Novotny M., Pickova D., Zarsky V.;
RT "Formin homology 2 domains occur in multiple contexts in angiosperms.";
RL BMC Genomics 5:44-44(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF07004.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP003349; BAC06896.1; -; Genomic_DNA.
DR EMBL; AP003418; BAB86073.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF07004.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014957; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AK061290; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015629035.1; XM_015773549.1.
DR AlphaFoldDB; Q8S0F0; -.
DR SMR; Q8S0F0; -.
DR STRING; 4530.OS01T0897700-01; -.
DR PaxDb; Q8S0F0; -.
DR PRIDE; Q8S0F0; -.
DR GeneID; 4325107; -.
DR KEGG; osa:4325107; -.
DR eggNOG; KOG1922; Eukaryota.
DR InParanoid; Q8S0F0; -.
DR OrthoDB; 1204639at2759; -.
DR PlantReactome; R-OSA-9639861; Development of root hair.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; -; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213; PTHR23213; 2.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR PROSITE; PS51444; FH2; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..960
FT /note="Formin-like protein 1"
FT /id="PRO_0000318994"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 497..929
FT /note="FH2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00774"
FT REGION 39..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 208..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..76
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 301..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..385
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..406
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..437
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 722
FT /note="A -> V (in Ref. 5; AK061290)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 960 AA; 101642 MW; DE1C9DC176B66609 CRC64;
MPSLRRFLEL VVVGIVVCGV NGGSDGLEVA VARRQLHQPF FPDQSSSPPT PAPPGPAPPF
FPALPVPPPP PATAGQEQPT YPALVLPNTG AGGAAATAAP DGGGGGGGGA RKSKSSASKL
VPAIVLPLLT VAVLGLSIAF FFTHRRGNAA RGGGGGGGCV GGGDAKFLHP ERASLFARDE
FGGSGGAAAP PAAAMDYRYV GNAGIGRMDE KSSETTSSGD EASRSTGGSP ELRPLPPLLA
RQCGPMGARS PGSGVGGFAS PSSGDEEFYS PQGSSKMSTS HRTLAAAVEA AVAARDRSKS
PSPGSIVSTP SYPSSPGATM SPAPASPPLF SSPGQSGRRS VKSRSDSVRT FGQPPAPPPP
PPFAPTLPPP PPPRRKPPSP SPPSSPLIEN TSALRSTTTT DTTIPRNPFV QPPPPPTHTH
GPPPPPPPPP PPPVGYWESR VRKPGTGTSK ETRSPALSPP PQAASFKSGL PTDAFPGRLA
DNADHAAAAA AGGGGDKSEE TTPRPKLKPL HWDKVRASSD RVMVWDQLKS SSFQVNEEMI
ETLFICNPAN SAPPKEPATR RPVLPTPKTD NKVLDPKKSQ NIAILLRALN VSKEQVCDAL
CEGNTENFGA ELLETLLKMA PTKEEEIKLR EFKEETSPIK LGPAEKFLKA VLDIPFAFKR
VDAMLYIANF ESEVNYLKKS FETLETACDE LRNSRLFLKL LEAVLKTGNR MNVGTNRGDA
HAFKLDTLLK LVDVKGTDGK TTLLHFVVQE IIRTEGSHLS ASNQSTPRTQ ANPLRDELEC
KKLGLQVVAG LGNELSNVKK AAAMDSDVLS SYVSKLAGGI EKITEVLRLN EEVKSREDAW
RFHDSMQKFL KRADDDIIRV QAQESVALSL VKEITEYFHG DSAKEEAHPF RIFMVVRDFL
SVLDQVCKEV GRINDRTIAS SVRHFPVPVN PMMPQLFPRI HALRAGISDD ESSATSASSP
