FH2_ORYSI
ID FH2_ORYSI Reviewed; 833 AA.
AC A2XUA1;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Formin-like protein 2;
DE AltName: Full=OsFH2;
DE Flags: Precursor;
GN Name=FH2; ORFNames=OsI_015644;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [2]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15256004; DOI=10.1186/1471-2164-5-44;
RA Cvrckova F., Novotny M., Pickova D., Zarsky V.;
RT "Formin homology 2 domains occur in multiple contexts in angiosperms.";
RL BMC Genomics 5:44-44(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the formin-like family. Class-I subfamily.
CC {ECO:0000305}.
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DR EMBL; CM000129; EAY94411.1; -; Genomic_DNA.
DR AlphaFoldDB; A2XUA1; -.
DR SMR; A2XUA1; -.
DR STRING; 39946.A2XUA1; -.
DR EnsemblPlants; BGIOSGA014956-TA; BGIOSGA014956-PA; BGIOSGA014956.
DR Gramene; BGIOSGA014956-TA; BGIOSGA014956-PA; BGIOSGA014956.
DR HOGENOM; CLU_007699_2_1_1; -.
DR OMA; AWNPVPN; -.
DR Proteomes; UP000007015; Chromosome 4.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR Gene3D; 1.20.58.2220; -; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR027643; Formin-like_plant.
DR PANTHER; PTHR23213; PTHR23213; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR PROSITE; PS51444; FH2; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..833
FT /note="Formin-like protein 2"
FT /id="PRO_0000318995"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 438..833
FT /note="FH2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00774"
FT REGION 26..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 254..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..49
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..228
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..381
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..434
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 833 AA; 88899 MW; 714D415AF4904FEA CRC64;
MSSSARGITL LCLLLIVSST VLHFSIGGGS NGEKRRDDGD GDGDDEKVRL LLGANALGER
DRRHGHGHGG GVSSAPAPAP APARAHLPPP LLHKNARLPD PVPGRVGLGH RRGNATAAHR
RRSEREGKKS TPLVVVAAGA ALSGAAAVLL VVLVVFLACR RFQRRAMPGA DQSGTNKVSF
DPGPDVFYLD AVKPYVEADH GGGGGVVKTA PELAGPKEEP RCEEEDSGVA LSDDGADSVH
SSCCFHSSHF SYSELRDTKP GSNGVSPSPS GRSRRRSSAP VTPSEKNKAA SPYSPQCPRT
PSNRERSSRA HSPSSSVSDL TSVSTSVVKD HEVRRAVHSL MFPEAQSGGA GHVKEDEAES
GNMRPPPPPP PPPPPPPPAV TQQQDVKTSC GPAVPPPPPP TPPPPPPLLA PKQQSSGGPI
LPPAPAPPPL FRPWAPAVGK NGAPLPKLKP LHWDKVRAAP NRRMVWDRIR SSSFELDEKM
IESLFGYNAR CSTKHEEVQS RSPSLGHHVL DTKRLQNFTI LMKAVSATAE QIFAALLHGN
GLSAQQLEAL IKMAPAKDEA DKLSAYDGDV DGLVPAERLL KVVLTIPCAF ARVEAMLYRE
TFADEVGHIR KSFEMLEEAC RELMSSKLFL KLLEAVLKTG NRMNVGTARG GAMAFKLDAL
LKLADVKGTD GKTTLLHFVV QEMTRSRAAE AADIAAGLGA ELTNVRKTAT VDLDVLTTSV
SGLSHGLSRI KELVGSDLSG DERNQCFVAF MAPFVAHAGE VIRELEDGER RVLAHVREIT
EYYHGDVGKD EASPLRIFVI VRDFLGMLER VCKEVRGAKN CHGGNPALNL NNV
