FH7_ORYSJ
ID FH7_ORYSJ Reviewed; 1385 AA.
AC Q6K8Z4; Q0DWU4;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Formin-like protein 7;
DE AltName: Full=OsFH7;
GN Name=FH7;
GN OrderedLocusNames=Os02g0794900,
GN LOC_Os02g55150/LOC_Os02g55160/LOC_Os02g55170; ORFNames=OJ1695_H09.6;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15256004; DOI=10.1186/1471-2164-5-44;
RA Cvrckova F., Novotny M., Pickova D., Zarsky V.;
RT "Formin homology 2 domains occur in multiple contexts in angiosperms.";
RL BMC Genomics 5:44-44(2004).
CC -!- SIMILARITY: Belongs to the formin-like family. Class-II subfamily.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD19266.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF10294.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP004094; BAD19266.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008208; BAF10294.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; Q6K8Z4; -.
DR SMR; Q6K8Z4; -.
DR STRING; 4530.OS02T0794900-00; -.
DR PaxDb; Q6K8Z4; -.
DR PRIDE; Q6K8Z4; -.
DR eggNOG; KOG1922; Eukaryota.
DR HOGENOM; CLU_002558_0_1_1; -.
DR InParanoid; Q6K8Z4; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q6K8Z4; OS.
DR GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.58.2220; -; 1.
DR Gene3D; 3.90.190.10; -; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR014020; Tensin_C2-dom.
DR Pfam; PF02181; FH2; 1.
DR Pfam; PF10409; PTEN_C2; 1.
DR SMART; SM00498; FH2; 1.
DR SMART; SM01326; PTEN_C2; 1.
DR SUPFAM; SSF52799; SSF52799; 1.
DR PROSITE; PS51182; C2_TENSIN; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51181; PPASE_TENSIN; 1.
PE 3: Inferred from homology;
KW Hydrolase; Protein phosphatase; Reference proteome.
FT CHAIN 1..1385
FT /note="Formin-like protein 7"
FT /id="PRO_0000319011"
FT DOMAIN 9..193
FT /note="Phosphatase tensin-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00590"
FT DOMAIN 199..358
FT /note="C2 tensin-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00589"
FT DOMAIN 974..1372
FT /note="FH2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00774"
FT REGION 345..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 427..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..989
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1362..1385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..668
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..703
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 704..721
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 724..833
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..857
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 894..908
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 918..934
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 969..983
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 126
FT /note="Phosphocysteine intermediate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00590"
SQ SEQUENCE 1385 AA; 151267 MW; DD307D820B05DFC4 CRC64;
MALFRKFFFK KPPDGLLLIT DNIYVFDHCF SMKEMEEDHF EAHIRGVAAH LLDNFGDHSF
MISNFGIRDE ESPIYHILSE YGMTVLDYPG HYEGCPLLTM EMVHCILKSS ESWLSLGQRN
FLIMHCEQGC WPILAFMLAA LLIYLGQYSD EQKTLDMLYK QSPVELLEMF SPLNPMPSQL
RYLRYVSMRN VVPEWPPADR ALTLDSVILR MVPDFHGQGG FRPIFRIYGP DPLMPTDQTP
KVLFSTPKRS NVVRFYSQAD ELVKINLQCH VQGDVVLECI NLYEDLDRED MVIFSDMDAT
TSHITTEPVS HQEKQGLGIE EFAKVLDIFN HLDWLDGKKD TSLHIPQRKA SSTSQGNIDE
SPADGSETFF DTKEELDFDS LSGESSSSLV LKLTDDYVMV GCTELQQDPL HSTSAEVPSK
IQTIEVAPSR TRPPSVLLSP TKVKMPKTSA SSMALPSSTV IPQAPSSPVQ PQGLIDSAVQ
IAPAQSASKS AENSGSQTPV NQEPSPLTVN NSASTASLIA LCTPPPLPPP PPTVSLAPVS
PILPINTSTS IISVSLRSIM PSPSQPPESS ASPLALARNE ELVKSQEPSC ENLEKFPPEF
SRASSVTALS SDSLLSIEKE SSSTRTYVPE ALPAMPLTSD TRTSLISIST AASPPLPPPL
PPPLKPSTVM FPLSYGKEVA STKEKAAPTQ PPLPPPPPPI QPTLISNSIY SSTSSVVSAP
LKRGQSPAPP PPPPPPPPPP FPVSSFSPPQ PPPQPPSAVP GLQASPVPPP PPPPPPPMIP
GMKTPPTPPP PPPAAPGQQA PAVPPPPPPP PPPMVPGMQT RPIPPPPPPS QTNSLVSSFP
STSKRIPPPP PPPSQTSSLV SSLPSSRKGN DVAAPRPPPP PPLYSRSSHV TSAPSAPPAP
PLPPPKLVGA SKPSQEQMIT WPPPPPPGPP PKNSSNSLPS KGNVVSSSPP PPPTFSFGAK
DRSTARSRSP RSLRPNQSSK RTPLKPLHWV KVSRATQGSL WAETQKSDEA SRTPEIDISE
LESLFSVAMP NMEEKRARQR PSVAAKQEKV LLIDLQRSKN CEIMLRNIKM PLPDLMNSVL
ALDDSIVDGD QVDYLIKFCP TKEEMELLKG FTGNKENLGK CEQFFLEMMK VPRVESKLRI
LSFKIKFLTQ VADLKNSLNT INSVAEEVRN SVKLKRVMQT ILSLGNALNQ GTARGSAVGF
RLDSLLKLID IRARNNRMTL MHYLCKVLSD KLPEVLDFNK DLTYLEPASK IQLKELAEEM
QAITKGLEKV EQELTTSEKD GPGSEIFYKK LKEFLADAQA EGRSLAFLYS TAGKSADSLA
HYFGEDPVRC PFEQVVSTLL SFVKTFERAH AENLRQMELE KKRAQMEAEK EKVKAAAHKE
DLLEP
