ID   FHAB_MYCS2              Reviewed;         155 AA.
AC   A0QNG6;
DT   31-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=FHA domain-containing protein FhaB;
DE   AltName: Full=FtsZ-interacting protein A;
GN   Name=fhaB; Synonyms=fipA; OrderedLocusNames=MSMEG_0034, MSMEI_0036;
OS   Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS   smegmatis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=246196;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA   Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA   Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT   "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT   mutations or sequencing errors?";
RL   Genome Biol. 8:R20.1-R20.9(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=18955433; DOI=10.1101/gr.081901.108;
RA   Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA   Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT   "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT   and a new MS-based protocol.";
RL   Genome Res. 19:128-135(2009).
RN   [4]
RP   RETRACTED PAPER.
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=20066037; DOI=10.1371/journal.pone.0008590;
RA   Sureka K., Hossain T., Mukherjee P., Chatterjee P., Datta P., Kundu M.,
RA   Basu J.;
RT   "Novel role of phosphorylation-dependent interaction between FtsZ and FipA
RT   in mycobacterial cell division.";
RL   PLoS ONE 5:E8590-E8590(2010).
RN   [5]
RP   RETRACTION NOTICE OF PUBMED:20066037.
RX   PubMed=35202441; DOI=10.1371/journal.pone.0264672;
RG   PLOS ONE Editors;
RL   PLoS ONE 17:e0264672-e0264672(2022).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:P9WJB5};
CC       Single-pass membrane protein {ECO:0000255}.
CC   -!- PTM: Phosphorylated by PknB (By similarity). Dephosphorylated by PstP
CC       (By similarity). {ECO:0000250|UniProtKB:P9WJB5}.
CC   -!- CAUTION: The article by Sureka et al was retracted by the editors after
CC       publication. Concerns were raised regarding the results presented in
CC       multiple figure panels. The raw data or replacement panels that were
CC       available did not satisfactorily address all the issues, thus
CC       questioning the integrity of the data. {ECO:0000305|PubMed:35202441}.
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DR   EMBL; CP000480; ABK74891.1; -; Genomic_DNA.
DR   EMBL; CP001663; AFP36519.1; -; Genomic_DNA.
DR   RefSeq; WP_011726620.1; NZ_SIJM01000001.1.
DR   RefSeq; YP_884454.1; NC_008596.1.
DR   AlphaFoldDB; A0QNG6; -.
DR   SMR; A0QNG6; -.
DR   STRING; 246196.MSMEI_0036; -.
DR   PRIDE; A0QNG6; -.
DR   EnsemblBacteria; ABK74891; ABK74891; MSMEG_0034.
DR   EnsemblBacteria; AFP36519; AFP36519; MSMEI_0036.
DR   GeneID; 66738225; -.
DR   KEGG; msg:MSMEI_0036; -.
DR   KEGG; msm:MSMEG_0034; -.
DR   PATRIC; fig|246196.19.peg.32; -.
DR   eggNOG; COG1716; Bacteria.
DR   OMA; GQWIVED; -.
DR   OrthoDB; 1687028at2; -.
DR   Proteomes; UP000000757; Chromosome.
DR   Proteomes; UP000006158; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd00060; FHA; 1.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   InterPro; IPR032030; YscD_cytoplasmic_dom.
DR   Pfam; PF16697; Yop-YscD_cpl; 1.
DR   SMART; SM00240; FHA; 1.
DR   SUPFAM; SSF49879; SSF49879; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..155
FT                   /note="FHA domain-containing protein FhaB"
FT                   /id="PRO_0000419672"
FT   TRANSMEM        6..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          83..132
FT                   /note="FHA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00086"
FT   MOD_RES         36
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:P9WJB5"
SQ   SEQUENCE   155 AA;  17125 MW;  C5994E935EDD1917 CRC64;
     MQGLVLQLTR VGFLLLLWLF IWSVLRILRT DIYAPTGAVM VRRGLALRGS LLPNRQRRHV
     ARQLVVTEGA LAGTRITLGN QPVLIGRADD STLVLTDDYA STRHARLSPR GSEWYVEDLG
     STNGTYLDRA KVTTAVKVPI GAPVRIGKTV IELRP