FHI2A_XENLA
ID FHI2A_XENLA Reviewed; 744 AA.
AC A0JPG1;
DT 17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 1.
DT 03-AUG-2022, entry version 31.
DE RecName: Full=FHF complex subunit HOOK interacting protein 2A;
DE Short=FHIP2A;
GN Name=fhip2a; Synonyms=fam160b1;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be required for proper functioning of the nervous system.
CC {ECO:0000250|UniProtKB:Q5W0V3}.
CC -!- SIMILARITY: Belongs to the FHIP family. {ECO:0000305}.
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DR EMBL; BC127407; AAI27408.1; -; mRNA.
DR RefSeq; NP_001090553.1; NM_001097084.1.
DR AlphaFoldDB; A0JPG1; -.
DR DNASU; 100036789; -.
DR GeneID; 100036789; -.
DR KEGG; xla:100036789; -.
DR CTD; 100036789; -.
DR Xenbase; XB-GENE-5894431; fhip2a.S.
DR OrthoDB; 266554at2759; -.
DR Proteomes; UP000186698; Chromosome 7S.
DR Bgee; 100036789; Expressed in internal ear and 19 other tissues.
DR InterPro; IPR019384; FHIP.
DR InterPro; IPR045669; FHIP_C.
DR InterPro; IPR045668; FHIP_KELAA_motif.
DR PANTHER; PTHR21705; PTHR21705; 1.
DR Pfam; PF19314; DUF5917; 1.
DR Pfam; PF19311; KELAA; 1.
DR Pfam; PF10257; RAI16-like; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..744
FT /note="FHF complex subunit HOOK interacting protein 2A"
FT /id="PRO_0000284651"
FT REGION 197..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 744 AA; 83911 MW; 22159588D9B268F0 CRC64;
MFSKISSILQ QAVEALAPSL PLQEDFVYHW KAITHYYIET SDDKAPVTDT NIPSHLEQML
DILVQEENER ESGETGPCME YLLHHKVLET LYTLGKADCP PGMKQQVLIF YTKLLGRIRQ
PLLPHINVHR PVQKLIRLCG EVLANPTENE EIQFLCIVCA KLKQDPYLVN FFLENKSKGA
QSGGYIFPGG SAQHELLNDT GQPERTVGAN ADPGNESSSG DLKPSASSEA SANHIQQDYN
LVNSLLNLTK SPDGRIAVKA CEGLMLLVSL PEVAAAKCLT QSTSLCQLLT DRLTSLYQAL
PHSIDPLDIE TVEGINWGLD SYSVKEDASA FPGKRALISF LSWFDYCDQL IKEAHRIAAS
AMARSVRERF LVGIMEPQLL QTSEIGILTA TALLHRIVRQ VTSKSLLEQI VYFILGEHRD
PETLRDVHKT PLRHRLIEHC NHISDEISIM TLRLFEHLLH KPNEHILYNL VLRNLEERNY
TEYKPPCPED KDIVENGQIP GAVDLEEDPI FTGMSPENTL SKEWLSASPP ITPEHHRTDG
KTEVHKIVNS FLCLVPDEAK SSYQVEGTGY DTYLRDAHRQ FREYCAICLR WDWPGAAKAI
DKCNLEAPFF EGHFLKVLFD RMGRILDQPY DVNLQVTSVL SKLSLFPHPH IHEFLLDPYV
NLAPGCRSLF SVIVRVVGDL MVRIQRIPEF TPKLLLVRKR LLGLEPDGPM VDHMTLLEGV
IVLEEFCKEL AAIAFVKYHS SSTP