ID   FIB37_BPT4              Reviewed;        1026 AA.
AC   P03744;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   29-SEP-2021, entry version 95.
DE   RecName: Full=Long-tail fiber protein gp37;
DE   AltName: Full=Gene product 37 {ECO:0000305};
DE            Short=gp37;
DE   AltName: Full=Receptor-recognizing protein;
GN   Name=37;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7338921; DOI=10.1016/0022-2836(81)90407-1;
RA   Oliver D.B., Crowther R.A.;
RT   "DNA sequence of the tail fibre genes 36 and 37 of bacteriophage T4.";
RL   J. Mol. Biol. 153:545-568(1981).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [3]
RP   FUNCTION, AND SUBUNIT.
RX   PubMed=8709154; DOI=10.1006/jmbi.1996.0436;
RA   Cerritelli M.E., Wall J.S., Simon M.N., Conway J.F., Steven A.C.;
RT   "Stoichiometry and domainal organization of the long tail-fiber of
RT   bacteriophage T4: a hinged viral adhesin.";
RL   J. Mol. Biol. 260:767-780(1996).
RN   [4] {ECO:0007744|PDB:2XGF}
RP   X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 785-1026.
RX   PubMed=21041684; DOI=10.1073/pnas.1011218107;
RA   Bartual S.G., Otero J.M., Garcia-Doval C., Llamas-Saiz A.L., Kahn R.,
RA   Fox G.C., van Raaij M.J.;
RT   "Structure of the bacteriophage T4 long tail fiber receptor-binding tip.";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:20287-20292(2010).
CC   -!- FUNCTION: Structural component of the distal-half of the long-tail
CC       fiber. It constitutes the part of the long-tail fibers that recognizes
CC       the bacterial receptor. The long-tail fiber of T4 is about 1600
CC       Angstroms long with a kink in the middle that divides the fiber into
CC       proximal and distal halves. The thin tip of the distal half-fiber
CC       interacts with the bacterial lipopolysaccharide receptor and specifies
CC       the host range of the phage. {ECO:0000269|PubMed:8709154}.
CC   -!- SUBUNIT: The long-tail fibers are trimeric, with a stoichiometry of
CC       gp34/gp37/gp36/gp35 of 3:3:3:1. {ECO:0000269|PubMed:8709154}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- MISCELLANEOUS: The two gp37 protein chains run in parallel, the length
CC       of the distal half-fiber, with the amino end near the center kink of
CC       the fiber and the carboxyl end at the distal tip. The other
CC       polypeptides are distributed uniformly along the length of the distal
CC       half-fiber.
CC   -!- SIMILARITY: Belongs to the tail fiber family. {ECO:0000305}.
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DR   EMBL; J02509; AAA32514.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42460.1; -; Genomic_DNA.
DR   PIR; A04369; TLBP74.
DR   RefSeq; NP_049863.1; NC_000866.4.
DR   PDB; 2XGF; X-ray; 2.20 A; A/B/C=785-1026.
DR   PDBsum; 2XGF; -.
DR   SMR; P03744; -.
DR   DIP; DIP-59477N; -.
DR   GeneID; 1258629; -.
DR   KEGG; vg:1258629; -.
DR   EvolutionaryTrace; P03744; -.
DR   Proteomes; UP000009087; Genome.
DR   GO; GO:0098024; C:virus tail, fiber; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0098671; P:adhesion receptor-mediated virion attachment to host cell; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1340.10; -; 1.
DR   InterPro; IPR005003; Phage_lambda_Stf-r1.
DR   InterPro; IPR011083; Phage_tail_collar_dom.
DR   InterPro; IPR037053; Phage_tail_collar_dom_sf.
DR   Pfam; PF07484; Collar; 1.
DR   Pfam; PF03335; Phage_fiber; 7.
PE   1: Evidence at protein level;
KW   3D-structure; Host-virus interaction; Late protein; Reference proteome;
KW   Viral attachment to host adhesion receptor; Viral attachment to host cell;
KW   Viral tail fiber protein; Viral tail protein; Virion;
KW   Virus entry into host cell.
FT   CHAIN           1..1026
FT                   /note="Long-tail fiber protein gp37"
FT                   /id="PRO_0000165026"
FT   REGION          905..927
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   STRAND          819..821
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          823..825
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          830..832
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   TURN            840..842
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   HELIX           844..849
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          862..865
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          887..889
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          896..898
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          906..909
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          918..922
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          932..937
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          943..947
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          952..959
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          969..973
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          983..985
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          992..994
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          1002..1004
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          1007..1011
FT                   /evidence="ECO:0007829|PDB:2XGF"
FT   STRAND          1015..1024
FT                   /evidence="ECO:0007829|PDB:2XGF"
SQ   SEQUENCE   1026 AA;  109225 MW;  965C1F01E308E1BC CRC64;
     MATLKQIQFK RSKIAGTRPA ASVLAEGELA INLKDRTIFT KDDSGNIIDL GFAKGGQVDG
     NVTINGLLRL NGDYVQTGGM TVNGPIGSTD GVTGKIFRST QGSFYARATN DTSNAHLWFE
     NADGTERGVI YARPQTTTDG EIRLRVRQGT GSTANSEFYF RSINGGEFQA NRILASDSLV
     TKRIAVDTVI HDAKAFGQYD SHSLVNYVYP GTGETNGVNY LRKVRAKSGG TIYHEIVTAQ
     TGLADEVSWW SGDTPVFKLY GIRDDGRMII RNSLALGTFT TNFPSSDYGN VGVMGDKYLV
     LGDTVTGLSY KKTGVFDLVG GGYSVASITP DSFRSTRKGI FGRSEDQGAT WIMPGTNAAL
     LSVQTQADNN NAGDGQTHIG YNAGGKMNHY FRGTGQMNIN TQQGMEINPG ILKLVTGSNN
     VQFYADGTIS SIQPIKLDNE IFLTKSNNTA GLKFGAPSQV DGTRTIQWNG GTREGQNKNY
     VIIKAWGNSF NATGDRSRET VFQVSDSQGY YFYAHRKAPT GDETIGRIEA QFAGDVYAKG
     IIANGNFRVV GSSALAGNVT MSNGLFVQGG SSITGQVKIG GTANALRIWN AEYGAIFRRS
     ESNFYIIPTN QNEGESGDIH SSLRPVRIGL NDGMVGLGRD SFIVDQNNAL TTINSNSRIN
     ANFRMQLGQS AYIDAECTDA VRPAGAGSFA SQNNEDVRAP FYMNIDRTDA SAYVPILKQR
     YVQGNGCYSL GTLINNGNFR VHYHGGGDNG STGPQTADFG WEFIKNGDFI SPRDLIAGKV
     RFDRTGNITG GSGNFANLNS TIESLKTDIM SSYPIGAPIP WPSDSVPAGF ALMEGQTFDK
     SAYPKLAVAY PSGVIPDMRG QTIKGKPSGR AVLSAEADGV KAHSHSASAS STDLGTKTTS
     SFDYGTKGTN STGGHTHSGS GSTSTNGEHS HYIEAWNGTG VGGNKMSSYA ISYRAGGSNT
     NAAGNHSHTF SFGTSSAGDH SHSVGIGAHT HTVAIGSHGH TITVNSTGNT ENTVKNIAFN
     YIVRLA