ID   3MGH_MYCTO              Reviewed;         203 AA.
AC   P9WJP6; L0TAC1; O33190; P65412;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=MT1727.1;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; AE000516; AAK45996.1; -; Genomic_DNA.
DR   PIR; G70501; G70501.
DR   RefSeq; WP_003408373.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJP6; -.
DR   SMR; P9WJP6; -.
DR   EnsemblBacteria; AAK45996; AAK45996; MT1727.1.
DR   GeneID; 45425657; -.
DR   KEGG; mtc:MT1727.1; -.
DR   PATRIC; fig|83331.31.peg.1854; -.
DR   HOGENOM; CLU_060471_3_1_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase.
FT   CHAIN           1..203
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000427793"
SQ   SEQUENCE   203 AA;  21340 MW;  9DFE3035819504B0 CRC64;
     MNAEELAIDP VAAAHRLLGA TIAGRGVRAM VVEVEAYGGV PDGPWPDAAA HSYRGRNGRN
     DVMFGPPGRL YTYRSHGIHV CANVACGPDG TAAAVLLRAA AIEDGAELAT SRRGQTVRAV
     ALARGPGNLC AALGITMADN GIDLFDPSSP VRLRLNDTHR ARSGPRVGVS QAADRPWRLW
     LTGRPEVSAY RRSSRAPARG ASD