ID   FIBIN_BOVIN             Reviewed;         211 AA.
AC   Q5E9H1;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Fin bud initiation factor homolog;
DE   Flags: Precursor;
GN   Name=FIBIN;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hippocampus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homodimer; disulfide-linked. Seems to also exist as monomers
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Golgi apparatus
CC       {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FIBIN family. {ECO:0000305}.
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DR   EMBL; BT020808; AAX08825.1; -; mRNA.
DR   EMBL; BT020949; AAX08966.1; -; mRNA.
DR   EMBL; BC122696; AAI22697.1; -; mRNA.
DR   RefSeq; NP_001015541.1; NM_001015541.1.
DR   AlphaFoldDB; Q5E9H1; -.
DR   SMR; Q5E9H1; -.
DR   STRING; 9913.ENSBTAP00000008771; -.
DR   PaxDb; Q5E9H1; -.
DR   PRIDE; Q5E9H1; -.
DR   Ensembl; ENSBTAT00000008771; ENSBTAP00000008771; ENSBTAG00000006676.
DR   GeneID; 507975; -.
DR   KEGG; bta:507975; -.
DR   CTD; 387758; -.
DR   VEuPathDB; HostDB:ENSBTAG00000006676; -.
DR   VGNC; VGNC:56527; FIBIN.
DR   eggNOG; ENOG502QSW0; Eukaryota.
DR   GeneTree; ENSGT00390000007623; -.
DR   HOGENOM; CLU_1323584_0_0_1; -.
DR   InParanoid; Q5E9H1; -.
DR   OMA; GFFCHLC; -.
DR   OrthoDB; 1323802at2759; -.
DR   TreeFam; TF331989; -.
DR   Proteomes; UP000009136; Chromosome 15.
DR   Bgee; ENSBTAG00000006676; Expressed in trachea and 98 other tissues.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0070528; P:protein kinase C signaling; IEA:Ensembl.
DR   GO; GO:0071548; P:response to dexamethasone; IEA:Ensembl.
DR   GO; GO:0010042; P:response to manganese ion; IEA:Ensembl.
DR   InterPro; IPR026772; Fibin.
DR   PANTHER; PTHR31185; PTHR31185; 1.
DR   Pfam; PF15819; Fibin; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Endoplasmic reticulum; Glycoprotein; Golgi apparatus;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000250"
FT   CHAIN           19..211
FT                   /note="Fin bud initiation factor homolog"
FT                   /id="PRO_0000349209"
FT   CARBOHYD        30
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        52
FT                   /note="Interchain"
FT                   /evidence="ECO:0000250"
FT   DISULFID        64
FT                   /note="Interchain"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   211 AA;  24233 MW;  07ABE7CD31FF1E52 CRC64;
     MVFLKFLWMG FLCHLCQGYF DGPLYPEMSN GTLHHYFVPD GDYEENDDPE KCQLLFRVSD
     HRRCSQGEGS SASTLLSLTL REEFTVLGRQ VEDAGRVLEG ISKSISYDLD GEESYGKYLR
     RESHQIGDAY SNSDKSLTEL ESKFKQGQEQ DSRQESRLNE DFLGMLVHTR SLLKETLDIS
     VGLRDKYELL ALTIRSHGTR LGRLKNDYLK V