FIBIN_RAT
ID FIBIN_RAT Reviewed; 217 AA.
AC Q5U2T4;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 07-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Fin bud initiation factor homolog;
DE Flags: Precursor;
GN Name=Fibin;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Brown Norway;
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Heart;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBUNIT: Homodimer; disulfide-linked. Seems to also exist as monomers
CC (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Golgi apparatus
CC {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FIBIN family. {ECO:0000305}.
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DR EMBL; CH473949; EDL79766.1; -; Genomic_DNA.
DR EMBL; BC085873; AAH85873.1; -; mRNA.
DR RefSeq; NP_001020213.1; NM_001025042.2.
DR AlphaFoldDB; Q5U2T4; -.
DR SMR; Q5U2T4; -.
DR STRING; 10116.ENSRNOP00000006203; -.
DR GlyGen; Q5U2T4; 1 site.
DR PaxDb; Q5U2T4; -.
DR Ensembl; ENSRNOT00000006203; ENSRNOP00000006203; ENSRNOG00000004699.
DR GeneID; 499856; -.
DR KEGG; rno:499856; -.
DR UCSC; RGD:1563711; rat.
DR CTD; 387758; -.
DR RGD; 1563711; Fibin.
DR eggNOG; ENOG502QSW0; Eukaryota.
DR GeneTree; ENSGT00390000007623; -.
DR HOGENOM; CLU_1323584_0_0_1; -.
DR InParanoid; Q5U2T4; -.
DR OMA; GFFCHLC; -.
DR OrthoDB; 1323802at2759; -.
DR PhylomeDB; Q5U2T4; -.
DR TreeFam; TF331989; -.
DR PRO; PR:Q5U2T4; -.
DR Proteomes; UP000002494; Chromosome 3.
DR Proteomes; UP000234681; Chromosome 3.
DR Bgee; ENSRNOG00000004699; Expressed in colon and 17 other tissues.
DR Genevisible; Q5U2T4; RN.
DR GO; GO:0005783; C:endoplasmic reticulum; ISO:RGD.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0042803; F:protein homodimerization activity; ISO:RGD.
DR GO; GO:0070528; P:protein kinase C signaling; ISO:RGD.
DR GO; GO:0071548; P:response to dexamethasone; ISO:RGD.
DR GO; GO:0010042; P:response to manganese ion; ISO:RGD.
DR InterPro; IPR026772; Fibin.
DR PANTHER; PTHR31185; PTHR31185; 1.
DR Pfam; PF15819; Fibin; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Endoplasmic reticulum; Glycoprotein; Golgi apparatus;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..18
FT /evidence="ECO:0000250"
FT CHAIN 19..217
FT /note="Fin bud initiation factor homolog"
FT /id="PRO_0000349213"
FT CARBOHYD 30
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 52
FT /note="Interchain"
FT /evidence="ECO:0000250"
FT DISULFID 64
FT /note="Interchain"
FT /evidence="ECO:0000250"
SQ SEQUENCE 217 AA; 24754 MW; 7187A56978D5D31B CRC64;
MMFTKLIWMG FFCHLCRGYF DGPLYPEMSN GTLHHYFVPD GDYEENDDPE KCQLLFRVSD
RRRCSQGEGG QASSLLSLTL REEFTVLGRQ VEDAGRVLEG ISKSISYDLD GEESYGKYLR
RESHQIGDAY SNSDKSLTEL ESKFKQGQEQ DSRQESRLNE DFLGMLVHTR SLLKETLGIS
VGLRDKYELL AHTIRSHGTR LGRLKSDYLE GGGQKMG
