ID   FIE1_MAIZE              Reviewed;         461 AA.
AC   Q8VZY7; Q84YB5;
DT   19-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Polycomb group protein FIE1;
DE   AltName: Full=Protein FERTILIZATION-INDEPENDENT ENDOSPERM 1;
GN   Name=FIE1;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC   TISSUE=Seed;
RX   PubMed=11950982; DOI=10.1104/pp.010742;
RA   Springer N.M., Danilevskaya O.N., Hermon P., Helentjaris T.G.,
RA   Phillips R.L., Kaeppler H.F., Kaeppler S.M.;
RT   "Sequence relationships, conserved domains, and expression patterns for
RT   maize homologs of the Polycomb group genes E(z), esc, and E(Pc).";
RL   Plant Physiol. 128:1332-1345(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND TISSUE SPECIFICITY.
RX   PubMed=12566582; DOI=10.1105/tpc.006759;
RA   Danilevskaya O.N., Hermon P., Hantke S., Muszynski M.G., Kollipara K.,
RA   Ananiev E.V.;
RT   "Duplicated fie genes in maize: expression pattern and imprinting suggest
RT   distinct functions.";
RL   Plant Cell 15:425-438(2003).
CC   -!- FUNCTION: Polycomb group (PcG) protein. PcG proteins act by forming
CC       multiprotein complexes, which are required to maintain the
CC       transcriptionally repressive state of homeotic genes throughout
CC       development. PcG proteins are not required to initiate repression, but
CC       to maintain it during later stages of development. They probably act
CC       via the methylation of histones, rendering chromatin heritably changed
CC       in its expressibility (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Specifically expressed in kernel starting from 6
CC       days after pollination. {ECO:0000269|PubMed:11950982,
CC       ECO:0000269|PubMed:12566582}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in embryo and endosperm.
CC       {ECO:0000269|PubMed:11950982}.
CC   -!- SIMILARITY: Belongs to the WD repeat ESC family. {ECO:0000305}.
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DR   EMBL; AY061964; AAL35973.1; -; mRNA.
DR   EMBL; AY150645; AAO26659.1; -; Genomic_DNA.
DR   RefSeq; NP_001105181.1; NM_001111711.1.
DR   AlphaFoldDB; Q8VZY7; -.
DR   SMR; Q8VZY7; -.
DR   STRING; 4577.GRMZM2G118205_P01; -.
DR   PaxDb; Q8VZY7; -.
DR   PRIDE; Q8VZY7; -.
DR   EnsemblPlants; Zm00001eb173090_T001; Zm00001eb173090_P001; Zm00001eb173090.
DR   GeneID; 542075; -.
DR   Gramene; Zm00001eb173090_T001; Zm00001eb173090_P001; Zm00001eb173090.
DR   KEGG; zma:542075; -.
DR   MaizeGDB; 754919; -.
DR   eggNOG; KOG1034; Eukaryota.
DR   HOGENOM; CLU_032683_2_0_1; -.
DR   OMA; ECKSPIR; -.
DR   OrthoDB; 1191277at2759; -.
DR   Proteomes; UP000007305; Chromosome 4.
DR   ExpressionAtlas; Q8VZY7; baseline and differential.
DR   Genevisible; Q8VZY7; ZM.
DR   GO; GO:0035098; C:ESC/E(Z) complex; IBA:GO_Central.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Chromatin regulator; Developmental protein; Nucleus; Reference proteome;
KW   Repeat; Repressor; Transcription; Transcription regulation; WD repeat.
FT   CHAIN           1..461
FT                   /note="Polycomb group protein FIE1"
FT                   /id="PRO_0000050978"
FT   REPEAT          143..186
FT                   /note="WD 1"
FT   REPEAT          189..229
FT                   /note="WD 2"
FT   REPEAT          235..275
FT                   /note="WD 3"
FT   REPEAT          301..338
FT                   /note="WD 4"
FT   REPEAT          351..391
FT                   /note="WD 5"
FT   REPEAT          398..437
FT                   /note="WD 6"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          429..461
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..36
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        23
FT                   /note="T -> P (in Ref. 2; AAO26659)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        40
FT                   /note="Q -> H (in Ref. 2; AAO26659)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        447..450
FT                   /note="Missing (in Ref. 2; AAO26659)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   461 AA;  50573 MW;  6FE70DB4D32AE755 CRC64;
     MPPSKARRKR SLRDITATVA TGTVANSKPG SSSTNEGKQQ DKKKEGPQEP DIPPLPPVVV
     NIVPRQGLGC EVVEGLLVPS RKREYKPNSK YTVGNHPIYA IGFNFIDMRY YDVFAIASCN
     SVIIYRCLEN GGFGLLQNYV DEDKDESFYT LSWTIDQVDS SPLLVAAGSN RIIRVINCAT
     EKLDKSLVGH GGSIHEIRTH ASKPSLIISA SKDESIRLWN VHTGICILVF AGAGGHRHDV
     LSVDFHPTEV GIFASCGMDN TVKIWSMKEF WIYVEKSYSW TGHPSKFPTR NIQFPVLTAA
     VHSDYVDCTR WLGDFILSKS VKNAVLLWEP KPDKRRPGEG SVDVLQKYPV PKCSLWFMKF
     SCDFYSNQMA IGNNKGEIYV WEVQSSPPVL IDRLCNQECK SPIRQTAVSF DGSTILGAAD
     DGAIWRWDEV DPAASSSKPD QAAAPAAGVG AGAGADADAD A