FIE1_ORYSJ
ID FIE1_ORYSJ Reviewed; 466 AA.
AC Q6ZJW8; C7J630;
DT 20-JUN-2018, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Polycomb group protein FIE1 {ECO:0000305};
DE AltName: Full=Protein FERTILIZATION-INDEPENDENT ENDOSPERM 1 {ECO:0000303|PubMed:19825651};
DE Short=OsFIE1 {ECO:0000303|PubMed:19825651};
DE AltName: Full=WD40 repeat-containing protein 154 {ECO:0000303|PubMed:22429805};
DE Short=OsWD40-154 {ECO:0000303|PubMed:22429805};
GN Name=FIE1 {ECO:0000303|PubMed:19825651};
GN OrderedLocusNames=Os08g0137250 {ECO:0000312|EMBL:BAT03753.1},
GN LOC_Os08g04290 {ECO:0000305};
GN ORFNames=OJ1613_G04.22 {ECO:0000312|EMBL:BAD03075.1},
GN OsJ_25973 {ECO:0000312|EMBL:EAZ41450.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP TISSUE SPECIFICITY, AND IMPRINTING.
RX PubMed=19825651; DOI=10.1093/mp/ssp036;
RA Luo M., Platten D., Chaudhury A., Peacock W.J., Dennis E.S.;
RT "Expression, imprinting, and evolution of rice homologs of the polycomb
RT group genes.";
RL Mol. Plant 2:711-723(2009).
RN [7]
RP GENE FAMILY, NOMENCLATURE, AND TISSUE SPECIFICITY.
RX PubMed=22429805; DOI=10.1186/1471-2164-13-100;
RA Ouyang Y., Huang X., Lu Z., Yao J.;
RT "Genomic survey, expression profile and co-expression network analysis of
RT OsWD40 family in rice.";
RL BMC Genomics 13:100-100(2012).
RN [8]
RP FUNCTION, SUBUNIT, AND INTERACTION WITH EZ1 AND CLF.
RX PubMed=23150632; DOI=10.1105/tpc.112.102269;
RA Zhang L., Cheng Z., Qin R., Qiu Y., Wang J.L., Cui X., Gu L., Zhang X.,
RA Guo X., Wang D., Jiang L., Wu C.Y., Wang H., Cao X., Wan J.;
RT "Identification and characterization of an epi-allele of FIE1 reveals a
RT regulatory linkage between two epigenetic marks in rice.";
RL Plant Cell 24:4407-4421(2012).
RN [9]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=27133784; DOI=10.1111/tpj.13202;
RA Huang X., Lu Z., Wang X., Ouyang Y., Chen W., Xie K., Wang D., Luo M.,
RA Luo J., Yao J.;
RT "Imprinted gene OsFIE1 modulates rice seed development by influencing
RT nutrient metabolism and modifying genome H3K27me3.";
RL Plant J. 87:305-317(2016).
CC -!- FUNCTION: Polycomb group (PcG) protein. PcG proteins act by forming
CC multiprotein complexes, which are required to maintain the
CC transcriptionally repressive state of homeotic genes throughout
CC development. PcG proteins are not required to initiate repression, but
CC to maintain it during later stages of development. They act via the
CC methylation of histones, rendering chromatin heritably changed in its
CC expressibility (PubMed:23150632, PubMed:27133784). Together with EZ1
CC and CLF forms a complex that is involved in gene transcriptional
CC repression by trimethylation on histone H3 'Lys-27' (H3K27me3) of
CC target genes (PubMed:23150632). Involved in the regulation of embryo
CC and seed endosperm development. FIE1-containing PcG complex in seed
CC endosperm regulates the expression of various transcription factors by
CC trimethylation on histone H3 'Lys-27' (H3K27me3) of target genes.
CC Involved in the overall expression regulation of nutrient metabolism
CC genes, such as prolamin synthesis and seed storage protein synthesis
CC genes. Can regulate valine, leucine and isoleucine metabolism-related
CC genes (PubMed:27133784). {ECO:0000269|PubMed:23150632,
CC ECO:0000269|PubMed:27133784}.
CC -!- SUBUNIT: Interacts with EZ1 and CLF (PubMed:23150632). Component of the
CC polycomb repressive complex 2 (PRC2), which methylates 'Lys-27'
CC residues of histone H3 (H3K27me3), leading to transcriptional
CC repression of the affected target gene (PubMed:23150632).
CC {ECO:0000269|PubMed:23150632}.
CC -!- TISSUE SPECIFICITY: Expressed specifically in seed endosperm.
CC {ECO:0000269|PubMed:19825651, ECO:0000269|PubMed:22429805,
CC ECO:0000269|PubMed:27133784}.
CC -!- MISCELLANEOUS: The FIE1 locus is imprinted. Maternal inherited gene is
CC expressed in the ovule (the egg and the central cell), while the
CC paternal inherited gene is silenced in the pollen. After fertilization,
CC only the maternal inherited allele is expressed (PubMed:19825651). The
CC gain-of-function epi-allele (Epi-df) plants exhibit dwarf phenotype,
CC defect in flower development and very poor seed set (PubMed:23150632).
CC Plants silencing FIE1 have delayed embryo development, reduced seed
CC set, and reduced grain length, width and weight (PubMed:27133784).
CC {ECO:0000269|PubMed:19825651, ECO:0000269|PubMed:23150632,
CC ECO:0000269|PubMed:27133784}.
CC -!- SIMILARITY: Belongs to the WD repeat ESC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAH94100.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP003896; BAD03075.1; -; Genomic_DNA.
DR EMBL; AP008214; BAH94100.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014964; BAT03753.1; -; Genomic_DNA.
DR EMBL; CM000145; EAZ41450.1; -; Genomic_DNA.
DR EMBL; AK242200; BAH01221.1; -; mRNA.
DR RefSeq; XP_015649120.1; XM_015793634.1.
DR AlphaFoldDB; Q6ZJW8; -.
DR SMR; Q6ZJW8; -.
DR STRING; 4530.OS08T0137250-01; -.
DR PaxDb; Q6ZJW8; -.
DR PRIDE; Q6ZJW8; -.
DR EnsemblPlants; Os08t0137250-01; Os08t0137250-01; Os08g0137250.
DR GeneID; 9271694; -.
DR Gramene; Os08t0137250-01; Os08t0137250-01; Os08g0137250.
DR KEGG; osa:9271694; -.
DR eggNOG; KOG1034; Eukaryota.
DR HOGENOM; CLU_032683_2_0_1; -.
DR InParanoid; Q6ZJW8; -.
DR OMA; QTDVCVA; -.
DR OrthoDB; 1191277at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR GO; GO:0035098; C:ESC/E(Z) complex; IBA:GO_Central.
DR GO; GO:0031519; C:PcG protein complex; IDA:UniProtKB.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:UniProtKB.
DR GO; GO:0009960; P:endosperm development; IMP:UniProtKB.
DR GO; GO:0009908; P:flower development; IMP:UniProtKB.
DR GO; GO:0031507; P:heterochromatin assembly; IMP:UniProtKB.
DR GO; GO:0070734; P:histone H3-K27 methylation; IMP:UniProtKB.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0048316; P:seed development; IMP:UniProtKB.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF00400; WD40; 2.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 1: Evidence at protein level;
KW Chromatin regulator; Developmental protein; Differentiation;
KW Reference proteome; Repeat; Transcription; Transcription regulation;
KW WD repeat.
FT CHAIN 1..466
FT /note="Polycomb group protein FIE1"
FT /id="PRO_0000444461"
FT REPEAT 167..209
FT /note="WD 1"
FT /evidence="ECO:0000255"
FT REPEAT 212..252
FT /note="WD 2"
FT /evidence="ECO:0000255"
FT REPEAT 258..298
FT /note="WD 3"
FT /evidence="ECO:0000255"
FT REPEAT 324..361
FT /note="WD 4"
FT /evidence="ECO:0000255"
FT REPEAT 374..414
FT /note="WD 5"
FT /evidence="ECO:0000255"
FT REPEAT 421..460
FT /note="WD 6"
FT /evidence="ECO:0000255"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 51849 MW; 4F230794D8505052 CRC64;
MGPTSRNHKS SQKDVAPNEA KPPRYPQRNR SITASASASA FASPAVANSR VAKERPSSST
AGEGEPQETV LKLPSIPTLP ARMAKLVPLE GLGCEAAVGS LTPSREREYK VTNKHTEGRR
PVYAIVFNFL DVRYYDIFAT ACGPRLSTYR CLMNGKFALL QSYLDDDMNE SFFTVSWACD
IDGNPLLVAA GSTGIIRVIN CATEKIYKSL VGHGGSVNEI KSQPSNPSLI ISASKDESIK
LWNVQTGILI LVFGGVGGHR HEVLGVDFHT SDIYRFLSCG MDNTVRIWSM KEFWEYVEKS
YSWTDATSKF PTKFVQFPVL CAEIHSNYVD CTKWLGDFVL SKSVENEILL WESITKEENP
GEGHIDVLQK YPVPECNIWF MKFSCDFHHN QLAIGNRDGK VYVWKVQTSP PVLIARLNNP
QVKSAIRQTA VSFDGSTILA CTEDGNIWRW DEVDHPTAPV PSKKQK
