ID   FIE2_MAIZE              Reviewed;         379 AA.
AC   Q8VZY6;
DT   19-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Polycomb group protein FIE2;
DE   AltName: Full=Protein FERTILIZATION-INDEPENDENT ENDOSPERM 2;
GN   Name=FIE2;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC   TISSUE=Seed;
RX   PubMed=11950982; DOI=10.1104/pp.010742;
RA   Springer N.M., Danilevskaya O.N., Hermon P., Helentjaris T.G.,
RA   Phillips R.L., Kaeppler H.F., Kaeppler S.M.;
RT   "Sequence relationships, conserved domains, and expression patterns for
RT   maize homologs of the Polycomb group genes E(z), esc, and E(Pc).";
RL   Plant Physiol. 128:1332-1345(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RX   PubMed=12566582; DOI=10.1105/tpc.006759;
RA   Danilevskaya O.N., Hermon P., Hantke S., Muszynski M.G., Kollipara K.,
RA   Ananiev E.V.;
RT   "Duplicated fie genes in maize: expression pattern and imprinting suggest
RT   distinct functions.";
RL   Plant Cell 15:425-438(2003).
CC   -!- FUNCTION: Polycomb group (PcG) protein. PcG proteins act by forming
CC       multiprotein complexes, which are required to maintain the
CC       transcriptionally repressive state of homeotic genes throughout
CC       development. PcG proteins are not required to initiate repression, but
CC       to maintain it during later stages of development. They probably act
CC       via the methylation of histones, rendering chromatin heritably changed
CC       in its expressibility (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Widely expressed. Expressed in the embryo sac
CC       before pollination. After pollination, its expression persists,
CC       predominantly in the embryo and at lower levels in the endosperm.
CC       {ECO:0000269|PubMed:11950982, ECO:0000269|PubMed:12566582}.
CC   -!- SIMILARITY: Belongs to the WD repeat ESC family. {ECO:0000305}.
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DR   EMBL; AY061965; AAL35974.1; -; mRNA.
DR   EMBL; AY150644; AAO26658.1; -; mRNA.
DR   RefSeq; NP_001105182.1; NM_001111712.1.
DR   AlphaFoldDB; Q8VZY6; -.
DR   SMR; Q8VZY6; -.
DR   STRING; 4577.GRMZM2G148924_P05; -.
DR   PaxDb; Q8VZY6; -.
DR   PRIDE; Q8VZY6; -.
DR   EnsemblPlants; Zm00001eb416950_T001; Zm00001eb416950_P001; Zm00001eb416950.
DR   GeneID; 542076; -.
DR   Gramene; Zm00001eb416950_T001; Zm00001eb416950_P001; Zm00001eb416950.
DR   KEGG; zma:542076; -.
DR   MaizeGDB; 754920; -.
DR   eggNOG; KOG1034; Eukaryota.
DR   HOGENOM; CLU_032683_2_0_1; -.
DR   OMA; WSYDSVT; -.
DR   OrthoDB; 1191277at2759; -.
DR   Proteomes; UP000007305; Chromosome 10.
DR   ExpressionAtlas; Q8VZY6; baseline and differential.
DR   Genevisible; Q8VZY6; ZM.
DR   GO; GO:0035098; C:ESC/E(Z) complex; IBA:GO_Central.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 2.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Chromatin regulator; Nucleus; Reference proteome; Repeat; Repressor;
KW   Transcription; Transcription regulation; WD repeat.
FT   CHAIN           1..379
FT                   /note="Polycomb group protein FIE2"
FT                   /id="PRO_0000050979"
FT   REPEAT          85..128
FT                   /note="WD 1"
FT   REPEAT          131..171
FT                   /note="WD 2"
FT   REPEAT          177..217
FT                   /note="WD 3"
FT   REPEAT          243..280
FT                   /note="WD 4"
FT   REPEAT          292..333
FT                   /note="WD 5"
FT   REPEAT          340..378
FT                   /note="WD 6"
SQ   SEQUENCE   379 AA;  42502 MW;  714523B288285F29 CRC64;
     MAKLGPGQGL GCEAAEGSLV PSRKREYKPC GKHTEGKRPL YAIGFNFMDA RYYDVFATVG
     GNRVTTYRCL ENGSFALLQA YVDEDKDESF YTLSWARDHV DGSPLLVAAG SNGIIRVINC
     ATEKLAKSFV GHGDSINEIR TQPLKPSLII SASKDESVRL WNVHTGICIL IFAGAGGHRN
     EVLSVDFHPS DIERFASCGM DNTVKIWSMK EFWLYVDKSY SWTDLPSKFP TKYVQFPVLI
     AAVHSNYVDC TRWLGDFILS KSVDNEIVLW EPKTKEQSPG EGSIDILQKY PVPECDIWFI
     KFSCDFHFNQ LAIGNREGKI YVWEVQSSPP VLIARLYNQQ CKSPIRQTAV SFDGSTILGA
     GEDGTIWRWD EVDHPSSRN