ID   AKH_ANOSE               Reviewed;           8 AA.
AC   P84241; P25423;
DT   09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   09-NOV-2004, sequence version 1.
DT   02-JUN-2021, entry version 33.
DE   RecName: Full=Adipokinetic hormone;
DE            Short=AKH;
OS   Anoplotrupes stercorosus (Dor beetle) (Geotrupes stercorosus).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Coleoptera; Polyphaga; Scarabaeiformia;
OC   Geotrupidae; Anoplotrupes.
OX   NCBI_TaxID=260542;
RN   [1]
RP   PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AMIDATION AT TRP-8, AND
RP   SUBCELLULAR LOCATION.
RC   TISSUE=Corpora cardiaca;
RX   PubMed=2039445; DOI=10.1042/bj2750671;
RA   Gaede G.;
RT   "A unique charged tyrosine-containing member of the adipokinetic
RT   hormone/red-pigment-concentrating hormone peptide family isolated and
RT   sequenced from two beetle species.";
RL   Biochem. J. 275:671-677(1991).
CC   -!- FUNCTION: This hormone, released from cells in the corpora cardiaca,
CC       causes release of diglycerides from the fat body and stimulation of
CC       muscles to use these diglycerides as an energy source during energy-
CC       demanding processes.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:2039445}.
CC   -!- SIMILARITY: Belongs to the AKH/HRTH/RPCH family. {ECO:0000305}.
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DR   PIR; A58641; A58641.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007629; P:flight behavior; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR002047; Adipokinetic_hormone_CS.
DR   PROSITE; PS00256; AKH; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Flight; Hormone; Neuropeptide;
KW   Pyrrolidone carboxylic acid; Secreted.
FT   PEPTIDE         1..8
FT                   /note="Adipokinetic hormone"
FT                   /id="PRO_0000043418"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:2039445"
FT   MOD_RES         8
FT                   /note="Tryptophan amide"
FT                   /evidence="ECO:0000269|PubMed:2039445"
SQ   SEQUENCE   8 AA;  1022 MW;  867AB775AB544736 CRC64;
     QLNYSPDW