FILR2_METH6
ID FILR2_METH6 Reviewed; 155 AA.
AC G7WMP8;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 25-JAN-2012, sequence version 1.
DT 25-MAY-2022, entry version 46.
DE RecName: Full=Probable methanogenesis regulatory protein FilR2 {ECO:0000305};
GN Name=filR2 {ECO:0000303|PubMed:24748383};
GN OrderedLocusNames=Mhar_0447 {ECO:0000312|EMBL:AET63832.1};
OS Methanosaeta harundinacea (strain 6Ac).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanotrichales; Methanotrichaceae; Methanothrix.
OX NCBI_TaxID=1110509;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=6Ac;
RX PubMed=22590603; DOI=10.1371/journal.pone.0036756;
RA Zhu J., Zheng H., Ai G., Zhang G., Liu D., Liu X., Dong X.;
RT "The genome characteristics and predicted function of methyl-group
RT oxidation pathway in the obligate aceticlastic methanogens, Methanosaeta
RT spp.";
RL PLoS ONE 7:E36756-E36756(2012).
RN [2]
RP FUNCTION, INDUCTION, AND PHOSPHORYLATION.
RC STRAIN=6Ac;
RX PubMed=24748383; DOI=10.1371/journal.pone.0095502;
RA Li J., Zheng X., Guo X., Qi L., Dong X.;
RT "Characterization of an archaeal two-component system that regulates
RT methanogenesis in Methanosaeta harundinacea.";
RL PLoS ONE 9:E95502-E95502(2014).
CC -!- FUNCTION: Member of the two-component regulatory system FilI/FilRs,
CC which is involved in the regulation of methanogenesis.
CC {ECO:0000269|PubMed:24748383}.
CC -!- INDUCTION: Transcriptionally regulated by FilR1.
CC {ECO:0000269|PubMed:24748383}.
CC -!- PTM: Phosphorylated by FilI. {ECO:0000269|PubMed:24748383}.
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DR EMBL; CP003117; AET63832.1; -; Genomic_DNA.
DR AlphaFoldDB; G7WMP8; -.
DR SMR; G7WMP8; -.
DR EnsemblBacteria; AET63832; AET63832; Mhar_0447.
DR KEGG; mhi:Mhar_0447; -.
DR PATRIC; fig|1110509.7.peg.499; -.
DR HOGENOM; CLU_000445_69_17_2; -.
DR OMA; FEKFWFS; -.
DR Proteomes; UP000005877; Chromosome.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; SSF52172; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome; Transcription;
KW Transcription regulation; Two-component regulatory system.
FT CHAIN 1..155
FT /note="Probable methanogenesis regulatory protein FilR2"
FT /id="PRO_0000433372"
FT DOMAIN 18..142
FT /note="Response regulatory"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT MOD_RES 75
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 155 AA; 17705 MW; A15C5AA5B70A3E29 CRC64;
MSYGLDSGDV LEAEDPFIIL LVEDNNAHAM LIMRAFERLG FTGRIEWLRD GKAALDYLRL
HEGGGRSLPR MVLLDLRLPK VDGHEVLSQI KRSERLRAIP VVVLTTSTSD DDLRRAYSNH
VNSYLIKPLS FEDLKRTVEE IKEYWLGWNR SPGPA