FIM1C_BACUC
ID FIM1C_BACUC Reviewed; 303 AA.
AC A7UZ95;
DT 06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 40.
DE RecName: Full=Putative fimbrium subunit Fim1C;
DE Flags: Precursor;
GN Name=fim1C; ORFNames=BACUNI_00621 {ECO:0000312|EMBL:EDO55779.1};
OS Bacteroides uniformis (strain ATCC 8492 / DSM 6597 / CCUG 4942 / CIP 103695
OS / JCM 5828 / KCTC 5204 / NCTC 13054 / VPI 0061).
OC Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=411479;
RN [1] {ECO:0000312|EMBL:EDO55779.1, ECO:0000312|Proteomes:UP000004110}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8492 / DSM 6597 / CCUG 4942 / CIP 103695 / JCM 5828 / KCTC 5204
RC / NCTC 13054 / VPI 0061 {ECO:0000312|EMBL:EDO55779.1,
RC ECO:0000312|Proteomes:UP000004110};
RA Sudarsanam P., Ley R., Guruge J., Turnbaugh P.J., Mahowald M., Liep D.,
RA Gordon J.;
RT "Draft genome sequence of Bacteroides uniformis (ATCC 8492).";
RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP X-RAY CRYSTALLOGRAPHY (1.67 ANGSTROMS) OF 23-303, FUNCTION, SUBUNIT, AND
RP SUBCELLULAR LOCATION.
RC STRAIN=ATCC 8492 / DSM 6597 / CCUG 4942 / CIP 103695 / JCM 5828 / KCTC 5204
RC / NCTC 13054 / VPI 0061 {ECO:0000303|PubMed:27062925};
RX PubMed=27062925; DOI=10.1016/j.cell.2016.03.016;
RA Xu Q., Shoji M., Shibata S., Naito M., Sato K., Elsliger M.A., Grant J.C.,
RA Axelrod H.L., Chiu H.J., Farr C.L., Jaroszewski L., Knuth M.W.,
RA Deacon A.M., Godzik A., Lesley S.A., Curtis M.A., Nakayama K., Wilson I.A.;
RT "A distinct type of pilus from the human microbiome.";
RL Cell 165:690-703(2016).
CC -!- FUNCTION: Putative component of the fimbrium tip. Fimbriae are
CC filamentous appendages on the cell surface that mediate cell adhesion
CC and biofilm formation. {ECO:0000305|PubMed:27062925}.
CC -!- SUBUNIT: May be part of the fimbrial tip.
CC {ECO:0000305|PubMed:27062925}.
CC -!- SUBCELLULAR LOCATION: Fimbrium {ECO:0000305|PubMed:27062925}.
CC -!- SIMILARITY: Belongs to the bacteroidetes fimbrillin superfamily. Mfa-
CC like family. {ECO:0000305}.
CC -!- CAUTION: Lacks the lipidation signal found in other family members,
CC suggesting it may not be exported to the cell surface, and may not be
CC part of the fimbriae. {ECO:0000305}.
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DR EMBL; AAYH02000035; EDO55779.1; -; Genomic_DNA.
DR RefSeq; WP_005825443.1; NZ_DS362236.1.
DR PDB; 4K4K; X-ray; 1.67 A; A/B=23-303.
DR PDBsum; 4K4K; -.
DR AlphaFoldDB; A7UZ95; -.
DR SMR; A7UZ95; -.
DR STRING; 411479.BACUNI_00621; -.
DR EnsemblBacteria; EDO55779; EDO55779; BACUNI_00621.
DR eggNOG; ENOG50331SI; Bacteria.
DR HOGENOM; CLU_071232_0_0_10; -.
DR OrthoDB; 1571554at2; -.
DR Proteomes; UP000004110; Unassembled WGS sequence.
DR GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.2620; -; 1.
DR InterPro; IPR025049; Mfa-like_1.
DR InterPro; IPR042278; Mfa-like_1_N.
DR Pfam; PF13149; Mfa_like_1; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Fimbrium; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000255"
FT CHAIN 23..303
FT /note="Putative fimbrium subunit Fim1C"
FT /id="PRO_5002714097"
FT STRAND 30..32
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 37..39
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 58..65
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 71..78
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 105..112
FT /evidence="ECO:0007829|PDB:4K4K"
FT TURN 119..121
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 122..126
FT /evidence="ECO:0007829|PDB:4K4K"
FT HELIX 133..135
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 139..147
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 153..155
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 158..171
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 173..175
FT /evidence="ECO:0007829|PDB:4K4K"
FT HELIX 178..181
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 185..191
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 194..198
FT /evidence="ECO:0007829|PDB:4K4K"
FT TURN 199..201
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 213..216
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 218..220
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 223..228
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 238..242
FT /evidence="ECO:0007829|PDB:4K4K"
FT HELIX 244..246
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 250..254
FT /evidence="ECO:0007829|PDB:4K4K"
FT HELIX 255..257
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 262..264
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 268..277
FT /evidence="ECO:0007829|PDB:4K4K"
FT STRAND 280..289
FT /evidence="ECO:0007829|PDB:4K4K"
SQ SEQUENCE 303 AA; 31832 MW; 7B90ABDFDCC3E6C8 CRC64;
MKKQALICAL LATVLLPGCS EDGENTPQPT DGRVALEATS GIRMNTRAYD KTWEAGDAIG
IYMLNGDATD GNGNRKYTTA QTAENGSFTA AEGQTIYFPV DASQRDFVAY YPYRETLADG
NVYTVDVSVQ TPQKDIDLMG AAKVEGKDKT DPKVAFVFTH KLVKLDITIK ADGTSLTDAD
LAGTTVSISN QQTAATYNVV TGGDATVTTG TTKEIVLHTD GLKAEGIVLP AASTAGMALT
FTVPGLEGQA FHWDVNSAAQ SKAFVAGSKY LYTITISKAG VEVSSKVEDW TPGNGGGETG
NAE