ID   FIM1C_ECOL6             Reviewed;         180 AA.
AC   P62606; P08561;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Type-1 fimbrial protein, C chain;
DE   AltName: Full=Type-1C pilin;
DE   Flags: Precursor;
GN   Name=pilC; Synonyms=focA; OrderedLocusNames=c1239;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Fimbriae (also called pili), polar filaments radiating from
CC       the surface of the bacterium to a length of 0.5-1.5 micrometers and
CC       numbering 100-300 per cell, enable bacteria to colonize the epithelium
CC       of specific host organs. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Fimbrium {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR   EMBL; AE014075; AAN79696.1; -; Genomic_DNA.
DR   RefSeq; WP_000768217.1; NC_004431.1.
DR   AlphaFoldDB; P62606; -.
DR   SMR; P62606; -.
DR   STRING; 199310.c1239; -.
DR   EnsemblBacteria; AAN79696; AAN79696; c1239.
DR   KEGG; ecc:c1239; -.
DR   eggNOG; COG3539; Bacteria.
DR   HOGENOM; CLU_088965_0_0_6; -.
DR   OMA; DAACAVN; -.
DR   BioCyc; ECOL199310:C1239-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1090; -; 1.
DR   InterPro; IPR000259; Adhesion_dom_fimbrial.
DR   InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   Pfam; PF00419; Fimbrial; 1.
DR   SUPFAM; SSF49401; SSF49401; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Fimbrium; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000250"
FT   CHAIN           24..180
FT                   /note="Type-1 fimbrial protein, C chain"
FT                   /id="PRO_0000009176"
FT   DISULFID        44..84
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   180 AA;  18328 MW;  337CF7A72859302F CRC64;
     MKLKFISMAV FSALTLGVAT NASAVTTVNG GTVHFKGEVV NAACAVNTNS FDQTVNLGQV
     RSERLKVDGA KSNPVGFTIE LNDCDSQVSA GAGIVFSGPA VTGKTDVLAL QSSAAGSATN
     VGVQITDHTG KVVPLDGTAS STFTLTDGTN KIPFQAVYYA TGQATAGIAN ADATFKVQYQ