ID   FIM1C_ECOLX             Reviewed;         180 AA.
AC   P62605; P08561;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1988, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Type-1 fimbrial protein, C chain;
DE   AltName: Full=Type-1C pilin;
DE   Flags: Precursor;
GN   Name=pilC; Synonyms=focA;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=AD110 / UPEC;
RX   PubMed=2861144; DOI=10.1016/0378-1119(85)90127-1;
RA   van Die I., van Geffen B., Hoekstra W., Bergmans H.;
RT   "Type 1C fimbriae of a uropathogenic Escherichia coli strain: cloning and
RT   characterization of the genes involved in the expression of the 1C antigen
RT   and nucleotide sequence of the subunit gene.";
RL   Gene 34:187-196(1985).
CC   -!- FUNCTION: Fimbriae (also called pili), polar filaments radiating from
CC       the surface of the bacterium to a length of 0.5-1.5 micrometers and
CC       numbering 100-300 per cell, enable bacteria to colonize the epithelium
CC       of specific host organs.
CC   -!- SUBCELLULAR LOCATION: Fimbrium.
CC   -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR   EMBL; AF298200; AAA23775.1; -; Genomic_DNA.
DR   RefSeq; WP_000768217.1; NZ_WIKS01000122.1.
DR   AlphaFoldDB; P62605; -.
DR   SMR; P62605; -.
DR   OMA; DAACAVN; -.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1090; -; 1.
DR   InterPro; IPR000259; Adhesion_dom_fimbrial.
DR   InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   Pfam; PF00419; Fimbrial; 1.
DR   SUPFAM; SSF49401; SSF49401; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Fimbrium; Signal.
FT   SIGNAL          1..23
FT   CHAIN           24..180
FT                   /note="Type-1 fimbrial protein, C chain"
FT                   /id="PRO_0000009175"
FT   DISULFID        44..84
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   180 AA;  18328 MW;  337CF7A72859302F CRC64;
     MKLKFISMAV FSALTLGVAT NASAVTTVNG GTVHFKGEVV NAACAVNTNS FDQTVNLGQV
     RSERLKVDGA KSNPVGFTIE LNDCDSQVSA GAGIVFSGPA VTGKTDVLAL QSSAAGSATN
     VGVQITDHTG KVVPLDGTAS STFTLTDGTN KIPFQAVYYA TGQATAGIAN ADATFKVQYQ