ID   FIMA1_SALTI             Reviewed;         184 AA.
AC   P37920;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 122.
DE   RecName: Full=Type-1 fimbrial protein, A chain;
DE   AltName: Full=Type-1A pilin;
DE   Flags: Precursor;
GN   Name=fimA; OrderedLocusNames=STY0589, t2320;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=STY4;
RX   PubMed=8288102; DOI=10.1111/j.1574-6968.1993.tb06583.x;
RA   Rossolini G.M., Muscas P., Chiesurin A., Satta G.;
RT   "Analysis of the Salmonella fim gene cluster: identification of a new gene
RT   (fimI) encoding a fimbrin-like protein and located downstream from the fimA
RT   gene.";
RL   FEMS Microbiol. Lett. 114:259-266(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Fimbriae (also called pili), polar filaments radiating from
CC       the surface of the bacterium to a length of 0.5-1.5 micrometers and
CC       numbering 100-300 per cell, enable bacteria to colonize the epithelium
CC       of specific host organs.
CC   -!- SUBCELLULAR LOCATION: Fimbrium.
CC   -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR   EMBL; X65168; CAA46286.1; -; Genomic_DNA.
DR   EMBL; AL513382; CAD05025.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO69914.1; -; Genomic_DNA.
DR   PIR; S20682; S20682.
DR   RefSeq; NP_455133.1; NC_003198.1.
DR   RefSeq; WP_000681037.1; NZ_WSUR01000008.1.
DR   AlphaFoldDB; P37920; -.
DR   SMR; P37920; -.
DR   STRING; 220341.16501808; -.
DR   EnsemblBacteria; AAO69914; AAO69914; t2320.
DR   KEGG; stt:t2320; -.
DR   KEGG; sty:STY0589; -.
DR   PATRIC; fig|220341.7.peg.592; -.
DR   eggNOG; COG3539; Bacteria.
DR   HOGENOM; CLU_088965_0_0_6; -.
DR   OMA; ATFVMKY; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1090; -; 1.
DR   InterPro; IPR000259; Adhesion_dom_fimbrial.
DR   InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   Pfam; PF00419; Fimbrial; 1.
DR   SUPFAM; SSF49401; SSF49401; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Fimbrium; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..184
FT                   /note="Type-1 fimbrial protein, A chain"
FT                   /id="PRO_0000009171"
FT   DISULFID        46..86
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   184 AA;  18793 MW;  E46BAD1A22468EB0 CRC64;
     MKHKLMTSTI ASLMFVAGAA VAADPTPVSV SGGTIHFEGK LVYAACAVST KSADQTVTLG
     QYRTASFTAI GDTTAQVPFS IVLNDCDPKV AATAAVAFSG QADNTNTNLL AVSSADNSTT
     ATGVGIEILD NTSSPLKPDG ATFSAKQALV EGTNTLRFTA RYKATAAATP GQANADATFI
     MKYE