ID   AKH_HELZE               Reviewed;           9 AA.
AC   P67787; P08901;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   02-JUN-2021, entry version 35.
DE   RecName: Full=Adipokinetic hormone;
DE   AltName: Full=Hez-AKH;
OS   Helicoverpa zea (Corn earworm moth) (Heliothis zea).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Heliothinae; Helicoverpa.
OX   NCBI_TaxID=7113;
RN   [1]
RP   PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AND AMIDATION AT GLY-9.
RX   PubMed=3964263; DOI=10.1016/0006-291x(86)90038-0;
RA   Jaffe H., Raina A.K., Riley C.T., Fraser B.A., Holman G.M., Wagner R.M.,
RA   Ridgway R.L., Hayes D.K.;
RT   "Isolation and primary structure of a peptide from the corpora cardiaca of
RT   Heliothis zea with adipokinetic activity.";
RL   Biochem. Biophys. Res. Commun. 135:622-628(1986).
CC   -!- FUNCTION: This hormone, released from cells in the corpora cardiaca,
CC       causes release of diglycerides from the fat body and stimulation of
CC       muscles to use these diglycerides as an energy source during energy-
CC       demanding processes.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the AKH/HRTH/RPCH family. {ECO:0000305}.
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DR   PIR; A24244; A24244.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007629; P:flight behavior; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR002047; Adipokinetic_hormone_CS.
DR   PROSITE; PS00256; AKH; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Flight; Hormone; Neuropeptide;
KW   Pyrrolidone carboxylic acid; Secreted.
FT   PEPTIDE         1..9
FT                   /note="Adipokinetic hormone"
FT                   /id="PRO_0000043420"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:3964263"
FT   MOD_RES         9
FT                   /note="Glycine amide"
FT                   /evidence="ECO:0000269|PubMed:3964263"
SQ   SEQUENCE   9 AA;  1026 MW;  403665A5A1A9D1A7 CRC64;
     QLTFTSSWG