ID   AKH_HEMMO               Reviewed;           8 AA.
AC   B3A0D3;
DT   06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2013, sequence version 1.
DT   11-DEC-2019, entry version 8.
DE   RecName: Full=Adipokinetic hormone {ECO:0000303|PubMed:22508719};
DE            Short=AKH {ECO:0000303|PubMed:22508719};
OS   Hemilobophasma montaguense (Gladiator) (Heel-walker).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Mantophasmatodea; Austrophasmatidae;
OC   Hemilobophasma.
OX   NCBI_TaxID=253130;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AND AMIDATION AT TRP-8.
RC   TISSUE=Corpora cardiaca {ECO:0000269|PubMed:22508719};
RX   PubMed=22508719; DOI=10.1093/sysbio/sys003;
RA   Predel R., Neupert S., Huetteroth W., Kahnt J., Waidelich D., Roth S.;
RT   "Peptidomics-based phylogeny and biogeography of Mantophasmatodea
RT   (Hexapoda).";
RL   Syst. Biol. 61:609-629(2012).
CC   -!- FUNCTION: This hormone, released from cells in the corpora cardiaca,
CC       causes release of diglycerides from the fat body and stimulation of
CC       muscles to use these diglycerides as an energy source during energy-
CC       demanding processes. {ECO:0000250|UniProtKB:P55319}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:22508719}.
CC   -!- SIMILARITY: Belongs to the AKH/HRTH/RPCH family. {ECO:0000255}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007629; P:flight behavior; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR002047; Adipokinetic_hormone_CS.
DR   PROSITE; PS00256; AKH; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Flight; Hormone; Neuropeptide;
KW   Pyrrolidone carboxylic acid; Secreted.
FT   PEPTIDE         1..8
FT                   /note="Adipokinetic hormone"
FT                   /evidence="ECO:0000269|PubMed:22508719"
FT                   /id="PRO_0000421653"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:22508719"
FT   MOD_RES         8
FT                   /note="Tryptophan amide"
FT                   /evidence="ECO:0000269|PubMed:22508719"
SQ   SEQUENCE   8 AA;  948 MW;  86786771A9C452D6 CRC64;
     QVNFTPGW