FIP1X_SCHPO
ID FIP1X_SCHPO Reviewed; 344 AA.
AC Q09801;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Pre-mRNA polyadenylation factor fip1;
GN ORFNames=SPAC22G7.10;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Pre-mRNA polyadenylation factor that directly interacts with
CC poly(A) polymerase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FIP1 family. {ECO:0000305}.
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DR EMBL; CU329670; CAA91134.1; -; Genomic_DNA.
DR PIR; T11620; T11620.
DR RefSeq; NP_593059.1; NM_001018457.2.
DR AlphaFoldDB; Q09801; -.
DR SMR; Q09801; -.
DR BioGRID; 278363; 10.
DR STRING; 4896.SPAC22G7.10.1; -.
DR iPTMnet; Q09801; -.
DR MaxQB; Q09801; -.
DR PaxDb; Q09801; -.
DR PRIDE; Q09801; -.
DR EnsemblFungi; SPAC22G7.10.1; SPAC22G7.10.1:pep; SPAC22G7.10.
DR GeneID; 2541873; -.
DR KEGG; spo:SPAC22G7.10; -.
DR PomBase; SPAC22G7.10; -.
DR VEuPathDB; FungiDB:SPAC22G7.10; -.
DR eggNOG; KOG1049; Eukaryota.
DR HOGENOM; CLU_765384_0_0_1; -.
DR InParanoid; Q09801; -.
DR OMA; GFNEYTW; -.
DR Reactome; R-SPO-159231; Transport of Mature mRNA Derived from an Intronless Transcript.
DR Reactome; R-SPO-72187; mRNA 3'-end processing.
DR Reactome; R-SPO-77595; Processing of Intronless Pre-mRNAs.
DR PRO; PR:Q09801; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0000785; C:chromatin; IDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:1990342; C:heterochromatin island; IDA:PomBase.
DR GO; GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IDA:PomBase.
DR GO; GO:1990251; C:nuclear exosome focus; IDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0031124; P:mRNA 3'-end processing; IMP:PomBase.
DR GO; GO:0006379; P:mRNA cleavage; ISO:PomBase.
DR GO; GO:0006378; P:mRNA polyadenylation; ISO:PomBase.
DR GO; GO:0071028; P:nuclear mRNA surveillance; IMP:PomBase.
DR GO; GO:0098789; P:pre-mRNA cleavage required for polyadenylation; IBA:GO_Central.
DR InterPro; IPR007854; Fip1_dom.
DR Pfam; PF05182; Fip1; 1.
PE 3: Inferred from homology;
KW mRNA processing; Nucleus; Reference proteome.
FT CHAIN 1..344
FT /note="Pre-mRNA polyadenylation factor fip1"
FT /id="PRO_0000215043"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..344
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 344 AA; 37290 MW; 571D391D0F88F27D CRC64;
MSNADQHMDV DEDEYLYGET IEERNDGVTV SNAKSPEQAS EESDDSDIEF IIETKPGERA
EPLGGSIATL GSTRPSAKPQ VEKTAVEVKT TEPQDLSTAE TAPKVDIDAV PTIDGKNIFE
IDLESFDDKP WRKPGADISD YFNYGFDEFT WAAYCAKQTT LRDDFSPQKF MASLAQIPGP
LPSGNVPSPA EFQAMMASGF PPFMPIPPPI GGPQEDMGYS RNFPVHASSN YNTTHTSGGG
VHSGAATPNA YVNNNPSSSR RESESPANSP NITSSAGMTH AQPTHNPTSS YGNGASTNYN
ASRPPSNHPH SSNYPSSSRR KPSPDRYSNY SSRGSGGRYR RNRY