FIP1_ASHGO
ID FIP1_ASHGO Reviewed; 323 AA.
AC Q751K8;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Pre-mRNA polyadenylation factor FIP1;
GN Name=FIP1; OrderedLocusNames=AGL307W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Pre-mRNA polyadenylation factor that directly interacts with
CC poly(A) polymerase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FIP1 family. {ECO:0000305}.
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DR EMBL; AE016820; AAS54184.1; -; Genomic_DNA.
DR RefSeq; NP_986360.1; NM_211422.1.
DR AlphaFoldDB; Q751K8; -.
DR SMR; Q751K8; -.
DR STRING; 33169.AAS54184; -.
DR EnsemblFungi; AAS54184; AAS54184; AGOS_AGL307W.
DR GeneID; 4622653; -.
DR KEGG; ago:AGOS_AGL307W; -.
DR eggNOG; KOG1049; Eukaryota.
DR HOGENOM; CLU_039307_2_1_1; -.
DR InParanoid; Q751K8; -.
DR OMA; GFNEYTW; -.
DR Proteomes; UP000000591; Chromosome VII.
DR GO; GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IBA:GO_Central.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; IEA:EnsemblFungi.
DR GO; GO:0003723; F:RNA binding; IEA:EnsemblFungi.
DR GO; GO:0006378; P:mRNA polyadenylation; IBA:GO_Central.
DR GO; GO:0098789; P:pre-mRNA cleavage required for polyadenylation; IBA:GO_Central.
DR InterPro; IPR007854; Fip1_dom.
DR Pfam; PF05182; Fip1; 1.
PE 3: Inferred from homology;
KW mRNA processing; Nucleus; Reference proteome.
FT CHAIN 1..323
FT /note="Pre-mRNA polyadenylation factor FIP1"
FT /id="PRO_0000238507"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..94
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..323
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 323 AA; 34218 MW; 317588ED119CE3FB CRC64;
MQLRAAQHLI AEELQMASSD DEDEKFLYGS EDEADGPRGQ QKRKLIPQGT AQIQEPDTKR
ARGADDGDVD MLDDDDEEED DDEDEDDEDS DSDVEIIIGT GADSSKLDSK ALTTPSTAAT
ATSAAESAIA PVSEQSAPVA AVQSGDSGAA MDKAVGALDI NAVGEYEGTP ITDIDPEVLK
EKPWRQPGAN LSDYFNYGFT EETWMEYLHK QEKLRKEYNP RKILMGLLAL QQQGKLGDGG
AGDGVMLSAG GMAHNDIKSP NKNNGSLPQP PAFPMGMPPM FGGFPPFPFP GMIPPNLGAA
SGNNGSGNHQ NMGTSSGNGN NGK
