ID   FIP1_ASPFU              Reviewed;         338 AA.
AC   Q4WM95;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Pre-mRNA polyadenylation factor fip1;
GN   Name=fip1; ORFNames=AFUA_6G10690;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: Pre-mRNA polyadenylation factor that directly interacts with
CC       poly(A) polymerase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FIP1 family. {ECO:0000305}.
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DR   EMBL; AAHF01000006; EAL88919.1; -; Genomic_DNA.
DR   RefSeq; XP_750957.1; XM_745864.1.
DR   AlphaFoldDB; Q4WM95; -.
DR   SMR; Q4WM95; -.
DR   STRING; 746128.CADAFUBP00007477; -.
DR   EnsemblFungi; EAL88919; EAL88919; AFUA_6G10690.
DR   GeneID; 3508262; -.
DR   KEGG; afm:AFUA_6G10690; -.
DR   VEuPathDB; FungiDB:Afu6g10690; -.
DR   eggNOG; KOG1049; Eukaryota.
DR   HOGENOM; CLU_039307_0_0_1; -.
DR   InParanoid; Q4WM95; -.
DR   OMA; FDEFTWE; -.
DR   OrthoDB; 1408696at2759; -.
DR   Proteomes; UP000002530; Chromosome 6.
DR   GO; GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IBA:GO_Central.
DR   GO; GO:0006378; P:mRNA polyadenylation; IBA:GO_Central.
DR   GO; GO:0098789; P:pre-mRNA cleavage required for polyadenylation; IBA:GO_Central.
DR   InterPro; IPR007854; Fip1_dom.
DR   Pfam; PF05182; Fip1; 1.
PE   3: Inferred from homology;
KW   mRNA processing; Nucleus; Reference proteome.
FT   CHAIN           1..338
FT                   /note="Pre-mRNA polyadenylation factor fip1"
FT                   /id="PRO_0000238508"
FT   REGION          1..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          282..338
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..59
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..102
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..151
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        289..311
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   338 AA;  36181 MW;  A1A4FD04243DE681 CRC64;
     MMMEDDDDDF YDPADAVPIN QAQDAPQNQS NEKSQELNEG EEQEEEIEVE EDEDDFNIIT
     EAPPDAPPPE VPHPRHANLR AEPQRPSSAD ISTKSVTPTV TPKLEAATPA PASARPTAPQ
     KPGSAYPPVQ ASTIDVNANP VHPSTGKPIL STDMDSDFPT EDDKPWRRPG SDISDYFNYG
     FDEFTWASYV LKQQELRKEV QDQKKQLDDM QNFLTMGLPP IPGAPGPAAP PGSAPPALPG
     MPGMPDIAPD MMQGMLASMM SQGMDPSSMD PMSFMQHAQA MMGGQGGAGA GQQQGQPGFG
     GQSQNSGFGG QGGGQPHMGF GGYDQRGGFG GRGRGRRW