ID   FIP1_CANAL              Reviewed;         326 AA.
AC   Q5AGC1; A0A1D8PNI5; Q5AGQ7;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Pre-mRNA polyadenylation factor FIP1;
GN   Name=FIP1; OrderedLocusNames=CAALFM_C502480WA;
GN   ORFNames=CaO19.11734, CaO19.4258;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Pre-mRNA polyadenylation factor that directly interacts with
CC       poly(A) polymerase. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FIP1 family. {ECO:0000305}.
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DR   EMBL; CP017627; AOW29673.1; -; Genomic_DNA.
DR   RefSeq; XP_720566.1; XM_715473.2.
DR   AlphaFoldDB; Q5AGC1; -.
DR   SMR; Q5AGC1; -.
DR   STRING; 237561.Q5AGC1; -.
DR   PRIDE; Q5AGC1; -.
DR   GeneID; 3637762; -.
DR   KEGG; cal:CAALFM_C502480WA; -.
DR   CGD; CAL0000182961; orf19.11734.
DR   VEuPathDB; FungiDB:C5_02480W_A; -.
DR   eggNOG; KOG1049; Eukaryota.
DR   HOGENOM; CLU_039307_2_0_1; -.
DR   InParanoid; Q5AGC1; -.
DR   OrthoDB; 1541076at2759; -.
DR   PRO; PR:Q5AGC1; -.
DR   Proteomes; UP000000559; Chromosome 5.
DR   GO; GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IBA:GO_Central.
DR   GO; GO:0006378; P:mRNA polyadenylation; IBA:GO_Central.
DR   GO; GO:0098789; P:pre-mRNA cleavage required for polyadenylation; IBA:GO_Central.
DR   InterPro; IPR007854; Fip1_dom.
DR   Pfam; PF05182; Fip1; 1.
PE   3: Inferred from homology;
KW   mRNA processing; Nucleus; Reference proteome.
FT   CHAIN           1..326
FT                   /note="Pre-mRNA polyadenylation factor FIP1"
FT                   /id="PRO_0000238509"
FT   REGION          1..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          215..267
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          302..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..49
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..69
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..138
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..256
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   326 AA;  35812 MW;  DF64CF9F4AC740A5 CRC64;
     MANSDDDDAF LYSDEEQEVE KQGPKVKRVK FADEESNKEE DKTNEKEQQQ QKQEASNSES
     GSGSGSESDS GSESDDDIDI IIRDTQPTKS KSSGTTIIGN EALSEMTDPE ESTSSSSTTA
     AAGTTTINKR QSSSTINLES VPRYQQEEDG EGDGTLITQL DIETLKLKPW RAPGVDVSDY
     FNYGFDEFTW LAYCHKQDKL RGEFNPQKVM ENIMKGPGGA VGANGTNGIN LGDKTGQQQQ
     QQQQQQQQQQ QQQPPQPPMG MMMPPPGFMA NMPMPPMGSM PPMPNMANMP NMANMPNMAN
     MPPPPPGFNG QFPAPYNIPH TMNQKQ