ID   3MGH_NATTJ              Reviewed;         198 AA.
AC   B2A7A8;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=Nther_0710;
OS   Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 /
OS   JW/NM-WN-LF).
OC   Bacteria; Firmicutes; Clostridia; Natranaerobiales; Natranaerobiaceae;
OC   Natranaerobius.
OX   NCBI_TaxID=457570;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J.;
RT   "Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-
RT   LF.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; CP001034; ACB84302.1; -; Genomic_DNA.
DR   RefSeq; WP_012447186.1; NC_010718.1.
DR   AlphaFoldDB; B2A7A8; -.
DR   SMR; B2A7A8; -.
DR   STRING; 457570.Nther_0710; -.
DR   EnsemblBacteria; ACB84302; ACB84302; Nther_0710.
DR   KEGG; nth:Nther_0710; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_0_2_9; -.
DR   OMA; VEAYHHT; -.
DR   OrthoDB; 1385409at2; -.
DR   Proteomes; UP000001683; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..198
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_1000127760"
SQ   SEQUENCE   198 AA;  22786 MW;  26135305799BA6DB CRC64;
     MKLDYEFFQR DAVSVAKDLI GKLLVRNLNG EELICRIVDT EAYCGPEDKG CHAYQNKRTN
     RTEVMYKSGG YVYVYLIYGL HYCFNVVVSK QDRPEAVFIR AGEPISGLKT MRDNRNIKSN
     KKTELTNGPG KLSQAMAIDK SLNGQDLVAS KEIYLRHACD SQSYQIIPAK RVNIDYAEEY
     TDKLWRFYIR DNPFVSIN