AKH_LIBAU
ID AKH_LIBAU Reviewed; 8 AA.
AC P25418;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1994, sequence version 2.
DT 26-FEB-2020, entry version 58.
DE RecName: Full=Adipokinetic hormone;
DE Short=AKH;
OS Libellula auripennis (Golden-winged skimmer dragonfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Palaeoptera; Odonata; Epiprocta; Anisoptera; Libellulidae; Libellula.
OX NCBI_TaxID=6966;
RN [1]
RP PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AMIDATION AT TRP-8, AND
RP SYNTHESIS.
RC TISSUE=Corpora cardiaca;
RX PubMed=2390213; DOI=10.1515/bchm3.1990.371.1.475;
RA Gaede G.;
RT "The putative ancestral peptide of the adipokinetic/red-pigment-
RT concentrating hormone family isolated and sequenced from a dragonfly.";
RL Biol. Chem. Hoppe-Seyler 371:475-483(1990).
CC -!- FUNCTION: This hormone, released from cells in the corpora cardiaca,
CC causes release of diglycerides from the fat body and stimulation of
CC muscles to use these diglycerides as an energy source during energy-
CC demanding processes.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the AKH/HRTH/RPCH family. {ECO:0000305}.
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DR PIR; S10596; S10596.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR GO; GO:0007629; P:flight behavior; IEA:UniProtKB-KW.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR InterPro; IPR002047; Adipokinetic_hormone_CS.
DR PROSITE; PS00256; AKH; 1.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Flight; Hormone; Neuropeptide;
KW Pyrrolidone carboxylic acid; Secreted.
FT PEPTIDE 1..8
FT /note="Adipokinetic hormone"
FT /id="PRO_0000043421"
FT MOD_RES 1
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000269|PubMed:2390213"
FT MOD_RES 8
FT /note="Tryptophan amide"
FT /evidence="ECO:0000269|PubMed:2390213"
SQ SEQUENCE 8 AA; 978 MW; 8665A771A9C452D6 CRC64;
QVNFTPSW