FIP1_EMENI
ID FIP1_EMENI Reviewed; 327 AA.
AC Q5BAJ7; C8VNZ9;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-NOV-2011, sequence version 2.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Pre-mRNA polyadenylation factor fip1;
GN Name=fip1; ORFNames=AN2433;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: Pre-mRNA polyadenylation factor that directly interacts with
CC poly(A) polymerase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FIP1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAA64139.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AACD01000040; EAA64139.1; ALT_SEQ; Genomic_DNA.
DR EMBL; BN001307; CBF86845.1; -; Genomic_DNA.
DR RefSeq; XP_660037.1; XM_654945.1.
DR AlphaFoldDB; Q5BAJ7; -.
DR SMR; Q5BAJ7; -.
DR STRING; 162425.CADANIAP00009145; -.
DR EnsemblFungi; CBF86845; CBF86845; ANIA_02433.
DR EnsemblFungi; EAA64139; EAA64139; AN2433.2.
DR GeneID; 2874664; -.
DR KEGG; ani:AN2433.2; -.
DR VEuPathDB; FungiDB:AN2433; -.
DR eggNOG; KOG1049; Eukaryota.
DR HOGENOM; CLU_039307_0_0_1; -.
DR InParanoid; Q5BAJ7; -.
DR OMA; FDEFTWE; -.
DR OrthoDB; 1580867at2759; -.
DR Proteomes; UP000000560; Chromosome VII.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IBA:GO_Central.
DR GO; GO:0006378; P:mRNA polyadenylation; IBA:GO_Central.
DR GO; GO:0098789; P:pre-mRNA cleavage required for polyadenylation; IBA:GO_Central.
DR InterPro; IPR007854; Fip1_dom.
DR Pfam; PF05182; Fip1; 1.
PE 3: Inferred from homology;
KW mRNA processing; Nucleus; Reference proteome.
FT CHAIN 1..327
FT /note="Pre-mRNA polyadenylation factor fip1"
FT /id="PRO_0000238512"
FT REGION 1..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..58
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 327 AA; 34752 MW; 3F3DBCEB7B1FEA96 CRC64;
MSHAMDDDDD DLYDPADAVP VTNPSDPRGP SADAPMNDNV EEEEEEVEED DEDDFNIITE
APPDAPPPET SHPRHANLRT ESQRPTSADS TSAQKSQTPT LTPKVDTSAS VPAGTRPTSQ
KPGSAYPPVH ASNIDVNANP VHPATGKPIL MTDMDADFPD DDKPWRRPGT DLTDYFNYGF
DEFTWASYVL KQQELRKEVG DQKRQLDDMQ NFLTMGLPPM PGAQPGAGPA AVSAPPPMPG
MPGIPDMNPD MMQGMLASMM SQGLDPSSMD PMSFMQHAQT MMGGQSGAGG GQQGQGGFGG
QGGGQSQMGY GNAGGGYGGG RGRGRRW