FIP1_GIBZE
ID FIP1_GIBZE Reviewed; 325 AA.
AC Q4IF44; A0A0E0S6J8; I1RJY0; V6R392;
DT 30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2012, sequence version 2.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Pre-mRNA polyadenylation factor FIP1;
GN Name=FIP1; ORFNames=FGRRES_04164, FGSG_04164;
OS Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084
OS / PH-1) (Wheat head blight fungus) (Fusarium graminearum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=229533;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=17823352; DOI=10.1126/science.1143708;
RA Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., Di Pietro A.,
RA Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., Antoniw J., Baldwin T.,
RA Calvo S.E., Chang Y.-L., DeCaprio D., Gale L.R., Gnerre S., Goswami R.S.,
RA Hammond-Kosack K., Harris L.J., Hilburn K., Kennell J.C., Kroken S.,
RA Magnuson J.K., Mannhaupt G., Mauceli E.W., Mewes H.-W., Mitterbauer R.,
RA Muehlbauer G., Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T.,
RA Qi W., Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M.,
RA Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.;
RT "The Fusarium graminearum genome reveals a link between localized
RT polymorphism and pathogen specialization.";
RL Science 317:1400-1402(2007).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=20237561; DOI=10.1038/nature08850;
RA Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT "Comparative genomics reveals mobile pathogenicity chromosomes in
RT Fusarium.";
RL Nature 464:367-373(2010).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1;
RX PubMed=26198851; DOI=10.1186/s12864-015-1756-1;
RA King R., Urban M., Hammond-Kosack M.C.U., Hassani-Pak K.,
RA Hammond-Kosack K.E.;
RT "The completed genome sequence of the pathogenic ascomycete fungus Fusarium
RT graminearum.";
RL BMC Genomics 16:544-544(2015).
CC -!- FUNCTION: Pre-mRNA polyadenylation factor that directly interacts with
CC poly(A) polymerase. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the FIP1 family. {ECO:0000305}.
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DR EMBL; DS231664; ESU08966.1; -; Genomic_DNA.
DR EMBL; HG970333; CEF79123.1; -; Genomic_DNA.
DR RefSeq; XP_011321465.1; XM_011323163.1.
DR AlphaFoldDB; Q4IF44; -.
DR SMR; Q4IF44; -.
DR STRING; 5518.FGSG_04164P0; -.
DR EnsemblFungi; ESU08966; ESU08966; FGSG_04164.
DR GeneID; 23551426; -.
DR KEGG; fgr:FGSG_04164; -.
DR eggNOG; KOG1049; Eukaryota.
DR HOGENOM; CLU_039307_1_0_1; -.
DR InParanoid; Q4IF44; -.
DR Proteomes; UP000070720; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR007854; Fip1_dom.
DR Pfam; PF05182; Fip1; 1.
PE 3: Inferred from homology;
KW mRNA processing; Nucleus; Reference proteome.
FT CHAIN 1..325
FT /note="Pre-mRNA polyadenylation factor FIP1"
FT /id="PRO_0000238513"
FT REGION 1..121
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..29
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..57
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..121
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 34514 MW; F0AA485EF26853AE CRC64;
MDIDEDDDLY QPEEPKLESA PAEDNKPKTD DLEEGEEEDE GAAMDEDDDD DDDSDIDIIT
ERKDGTKPAP PQQSKYSDIR NIPQRTASND MPAQPAPVKQ ESESRTSVNV AAPSADKTSA
AASKSTIDVN VNPIHPGTGK PITQVNIDEE NDKPWRKPGT DISDYFNYGF DEFTWALYAS
KQETVRGEFG ADVFAQNNKK MMEDFNMMMM GGMGMPGGGN SGGQQAGMSG GMDGMPPEMQ
AMMQQMMASG MDPSQMDPSQ MNAMFSGMQN AGGAGAQGAQ GGQGGNFGGG FGNNQGGFGY
DQNMSGGGGG GGRGGFGGRG RRGRW