FIS_ALIF1
ID FIS_ALIF1 Reviewed; 98 AA.
AC Q5E260;
DT 10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2005, sequence version 2.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=DNA-binding protein Fis {ECO:0000255|HAMAP-Rule:MF_00166};
GN Name=fis {ECO:0000255|HAMAP-Rule:MF_00166}; OrderedLocusNames=VF_2391;
OS Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Aliivibrio.
OX NCBI_TaxID=312309;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700601 / ES114;
RX PubMed=15703294; DOI=10.1073/pnas.0409900102;
RA Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R.,
RA Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E.,
RA Stevens A., Visick K., Whistler C., Greenberg E.P.;
RT "Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with
RT pathogenic congeners.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005).
CC -!- FUNCTION: Activates ribosomal RNA transcription. Plays a direct role in
CC upstream activation of rRNA promoters. {ECO:0000255|HAMAP-
CC Rule:MF_00166}.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00166}.
CC -!- SIMILARITY: Belongs to the transcriptional regulatory Fis family.
CC {ECO:0000255|HAMAP-Rule:MF_00166}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAW86886.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000020; AAW86886.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_005421285.1; NC_006840.2.
DR RefSeq; YP_205774.1; NC_006840.2.
DR AlphaFoldDB; Q5E260; -.
DR SMR; Q5E260; -.
DR STRING; 312309.VF_2391; -.
DR EnsemblBacteria; AAW86886; AAW86886; VF_2391.
DR GeneID; 64243777; -.
DR KEGG; vfi:VF_2391; -.
DR PATRIC; fig|312309.11.peg.2426; -.
DR eggNOG; COG2901; Bacteria.
DR HOGENOM; CLU_158040_3_0_6; -.
DR OrthoDB; 1933378at2; -.
DR Proteomes; UP000000537; Chromosome I.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR HAMAP; MF_00166; DNA_binding_Fis; 1.
DR InterPro; IPR005412; Fis_DNA-bd.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR Pfam; PF02954; HTH_8; 1.
DR PIRSF; PIRSF002097; DNA-binding_Fis; 1.
DR PRINTS; PR01591; DNABINDNGFIS.
DR PRINTS; PR01590; HTHFIS.
DR SUPFAM; SSF46689; SSF46689; 1.
PE 3: Inferred from homology;
KW Activator; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..98
FT /note="DNA-binding protein Fis"
FT /id="PRO_0000203899"
FT DNA_BIND 74..93
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00166"
SQ SEQUENCE 98 AA; 11047 MW; FC7FADB4861917DB CRC64;
MFDQSMTSEA LTVTTVTAQD QITQKPLRDS VKASLKNYLG QLNGQEVNDL YELVLAEVEQ
PLLDMIMQHT RGNQTKAANM MGINRGTLRK KLKKYGMN