ID   FIS_ALIF1               Reviewed;          98 AA.
AC   Q5E260;
DT   10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 2.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=DNA-binding protein Fis {ECO:0000255|HAMAP-Rule:MF_00166};
GN   Name=fis {ECO:0000255|HAMAP-Rule:MF_00166}; OrderedLocusNames=VF_2391;
OS   Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Aliivibrio.
OX   NCBI_TaxID=312309;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700601 / ES114;
RX   PubMed=15703294; DOI=10.1073/pnas.0409900102;
RA   Ruby E.G., Urbanowski M., Campbell J., Dunn A., Faini M., Gunsalus R.,
RA   Lostroh P., Lupp C., McCann J., Millikan D., Schaefer A., Stabb E.,
RA   Stevens A., Visick K., Whistler C., Greenberg E.P.;
RT   "Complete genome sequence of Vibrio fischeri: a symbiotic bacterium with
RT   pathogenic congeners.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:3004-3009(2005).
CC   -!- FUNCTION: Activates ribosomal RNA transcription. Plays a direct role in
CC       upstream activation of rRNA promoters. {ECO:0000255|HAMAP-
CC       Rule:MF_00166}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00166}.
CC   -!- SIMILARITY: Belongs to the transcriptional regulatory Fis family.
CC       {ECO:0000255|HAMAP-Rule:MF_00166}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAW86886.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000020; AAW86886.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_005421285.1; NC_006840.2.
DR   RefSeq; YP_205774.1; NC_006840.2.
DR   AlphaFoldDB; Q5E260; -.
DR   SMR; Q5E260; -.
DR   STRING; 312309.VF_2391; -.
DR   EnsemblBacteria; AAW86886; AAW86886; VF_2391.
DR   GeneID; 64243777; -.
DR   KEGG; vfi:VF_2391; -.
DR   PATRIC; fig|312309.11.peg.2426; -.
DR   eggNOG; COG2901; Bacteria.
DR   HOGENOM; CLU_158040_3_0_6; -.
DR   OrthoDB; 1933378at2; -.
DR   Proteomes; UP000000537; Chromosome I.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   HAMAP; MF_00166; DNA_binding_Fis; 1.
DR   InterPro; IPR005412; Fis_DNA-bd.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   Pfam; PF02954; HTH_8; 1.
DR   PIRSF; PIRSF002097; DNA-binding_Fis; 1.
DR   PRINTS; PR01591; DNABINDNGFIS.
DR   PRINTS; PR01590; HTHFIS.
DR   SUPFAM; SSF46689; SSF46689; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..98
FT                   /note="DNA-binding protein Fis"
FT                   /id="PRO_0000203899"
FT   DNA_BIND        74..93
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00166"
SQ   SEQUENCE   98 AA;  11047 MW;  FC7FADB4861917DB CRC64;
     MFDQSMTSEA LTVTTVTAQD QITQKPLRDS VKASLKNYLG QLNGQEVNDL YELVLAEVEQ
     PLLDMIMQHT RGNQTKAANM MGINRGTLRK KLKKYGMN