ID   FIS_ALISL               Reviewed;          98 AA.
AC   B6ENA5;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=DNA-binding protein Fis {ECO:0000255|HAMAP-Rule:MF_00166};
GN   Name=fis {ECO:0000255|HAMAP-Rule:MF_00166}; OrderedLocusNames=VSAL_I2839;
OS   Aliivibrio salmonicida (strain LFI1238) (Vibrio salmonicida (strain
OS   LFI1238)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Aliivibrio.
OX   NCBI_TaxID=316275;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LFI1238;
RX   PubMed=19099551; DOI=10.1186/1471-2164-9-616;
RA   Hjerde E., Lorentzen M.S., Holden M.T., Seeger K., Paulsen S., Bason N.,
RA   Churcher C., Harris D., Norbertczak H., Quail M.A., Sanders S.,
RA   Thurston S., Parkhill J., Willassen N.P., Thomson N.R.;
RT   "The genome sequence of the fish pathogen Aliivibrio salmonicida strain
RT   LFI1238 shows extensive evidence of gene decay.";
RL   BMC Genomics 9:616-616(2008).
CC   -!- FUNCTION: Activates ribosomal RNA transcription. Plays a direct role in
CC       upstream activation of rRNA promoters. {ECO:0000255|HAMAP-
CC       Rule:MF_00166}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00166}.
CC   -!- SIMILARITY: Belongs to the transcriptional regulatory Fis family.
CC       {ECO:0000255|HAMAP-Rule:MF_00166}.
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DR   EMBL; FM178379; CAQ80523.1; -; Genomic_DNA.
DR   RefSeq; WP_005421285.1; NC_011312.1.
DR   AlphaFoldDB; B6ENA5; -.
DR   SMR; B6ENA5; -.
DR   STRING; 316275.VSAL_I2839; -.
DR   EnsemblBacteria; CAQ80523; CAQ80523; VSAL_I2839.
DR   GeneID; 64243777; -.
DR   KEGG; vsa:VSAL_I2839; -.
DR   eggNOG; COG2901; Bacteria.
DR   HOGENOM; CLU_158040_3_0_6; -.
DR   OMA; MVLCEVE; -.
DR   OrthoDB; 1933378at2; -.
DR   Proteomes; UP000001730; Chromosome 1.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   HAMAP; MF_00166; DNA_binding_Fis; 1.
DR   InterPro; IPR005412; Fis_DNA-bd.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   Pfam; PF02954; HTH_8; 1.
DR   PIRSF; PIRSF002097; DNA-binding_Fis; 1.
DR   PRINTS; PR01591; DNABINDNGFIS.
DR   PRINTS; PR01590; HTHFIS.
DR   SUPFAM; SSF46689; SSF46689; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..98
FT                   /note="DNA-binding protein Fis"
FT                   /id="PRO_1000097450"
FT   DNA_BIND        74..93
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00166"
SQ   SEQUENCE   98 AA;  11047 MW;  FC7FADB4861917DB CRC64;
     MFDQSMTSEA LTVTTVTAQD QITQKPLRDS VKASLKNYLG QLNGQEVNDL YELVLAEVEQ
     PLLDMIMQHT RGNQTKAANM MGINRGTLRK KLKKYGMN