ID   AKH_PACMA               Reviewed;           8 AA.
AC   P84242; P25423;
DT   09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   09-NOV-2004, sequence version 1.
DT   02-JUN-2021, entry version 32.
DE   RecName: Full=Adipokinetic hormone;
DE            Short=AKH;
OS   Pachnoda marginata (Flower beetle).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Coleoptera; Polyphaga; Scarabaeiformia;
OC   Scarabaeidae; Cetoniinae; Pachnoda.
OX   NCBI_TaxID=7058;
RN   [1]
RP   PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AMIDATION AT TRP-8, AND
RP   SUBCELLULAR LOCATION.
RC   TISSUE=Corpora cardiaca;
RX   PubMed=1586453; DOI=10.1515/bchm3.1992.373.1.133;
RA   Gaede G., Lopata A., Kellner R., Rinehart K.L. Jr.;
RT   "Primary structures of neuropeptides isolated from the corpora cardiaca of
RT   various cetonid beetle species determined by pulsed-liquid phase sequencing
RT   and tandem fast atom bombardment mass spectrometry.";
RL   Biol. Chem. Hoppe-Seyler 373:133-142(1992).
CC   -!- FUNCTION: This hormone, released from cells in the corpora cardiaca,
CC       causes release of diglycerides from the fat body and stimulation of
CC       muscles to use these diglycerides as an energy source during energy-
CC       demanding processes.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:1586453}.
CC   -!- SIMILARITY: Belongs to the AKH/HRTH/RPCH family. {ECO:0000305}.
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DR   PIR; S21663; S21663.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0007629; P:flight behavior; IEA:UniProtKB-KW.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR002047; Adipokinetic_hormone_CS.
DR   PROSITE; PS00256; AKH; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Flight; Hormone; Neuropeptide;
KW   Pyrrolidone carboxylic acid; Secreted.
FT   PEPTIDE         1..8
FT                   /note="Adipokinetic hormone"
FT                   /id="PRO_0000043423"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:1586453"
FT   MOD_RES         8
FT                   /note="Tryptophan amide"
FT                   /evidence="ECO:0000269|PubMed:1586453"
SQ   SEQUENCE   8 AA;  1022 MW;  867AB775AB544736 CRC64;
     QLNYSPDW